N-(p-Toluenesulfonyl)urea

CAS: 1694-06-0

Ref. TR-T536040

Informação sobre produto

• Nome: N-(p-Toluenesulfonyl)urea
• Sinónimos: N-(p-Tolylsulfonyl)urea, Tosylurea, (p-Toluenesulfonyl)urea, (p-Tolylsulfonyl)urea, H 16650, N-(Aminocarbonyl)-4-methylbenzenesulfonamide, (p-Tolylsulfonyl)urea
• Marca: TRC

Descrição

Applications N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.
References Hellman, B., et al.: Metabol. Clinc. Experiment., 23, 839 (1974); Tozuka, Z., et al.: J. Pharma. Sci., 100, 4024 (2011);

Propriedades químicas

• Peso molecular: 214.242
• Fórmula: C₈H₁₀N₂O₃S
• Cor/forma: Neat
• InChI: InChI=1S/C8H10N2O3S/c1-6-2-4-7(5-3-6)14(12,13)10-8(9)11/h2-5H,1H3,(H3,9,10,11)