(3Beta,5Alpha,22Alpha,25R)-Tomatidine Hydrochloride

CAS: 511-98-8

Ref. TR-T538503

Informação sobre produto

• Nome: (3Beta,5Alpha,22Alpha,25R)-Tomatidine Hydrochloride
• Sinónimos: (3β,5α,22α,25R)-Spirosolan-3-ol Hydrochloride, Solasodanol Hydrochloride, 5.alpha.-Solasodan-3.beta.-ol, 5alpha-Solasodan-3beta-ol (8CI), Soladulcidine, spirosolan-3-ol, (3beta,5alpha,22alpha,25R)-

Descrição

Applications (3α,5β,22α,25R)-Tomatidine Hydrochloride, is an isomer of Tomatidine Hydrochloride (T538500), a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatidine protects against muscle atrophy and boosting muscle growth (see also Ursolic Acid U850100).
References Watkins, D.N., et al.: Nature, 422, 313 (2003); Chem. and Eng. News p 27, May 5 (2014)

• Marca: TRC

Propriedades químicas

• Peso molecular: 415.65 + (36.46)
• Fórmula: C₂₇H₄₅NO₂•HCl
• Cor/forma: Pale Beige to Light Beige Solid
• InChI: InChI=1S/C27H45NO2.ClH/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4;/h16-24,28-29H,5-15H2,1-4H3;1H/t16-,17+,18+,19+,20-,21+,22+,23+,24+,25+,26+,27-;/m1./s1
• Chave InChI: InChIKey=SXXHVPYRDFJKPG-FCQIFGPTSA-N
• SMILES: C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@@]32C)O[C@]12CC[C@@H](C)CN2.Cl