Trichlormethiazide

CAS: 133-67-5

Ref. TR-T774335

Informação sobre produto

• Nome: Trichlormethiazide
• Sinónimos: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide, 3-Dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 3-Dichloromethylhydrochlorothiazide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3-dichloromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Achletin, Anatran, Anistadin, Aponorin, Carvacron, Ciba 7057-Su, Diurazida, Diurese, Diuroral, Esmarin, Fluitran, Flurese, Flutra, Gangesol, Hydrotrichlorothiazide, Intromene, Kubacron, Metahydrin, Metatensin, NSC 61560, Nakva, Naqua, Naquasone, Naquival, Salirom, Tachionin, Tolcasone, Trichlormetazid, Trichlormethiazid, Trichloromethiazide, Triflumen, 6-Chloro-3-dichloromethyl-3, 4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide-1, 1-dioxide, Nsc 61560, Triclormetiazida, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide

Descrição

Applications Trichlormethiazide, is a diuretic, having similar properties as Hydrochlorothiazide (H714560). It is used for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension.
References Imamura, T., et al.: International Heart J., 54(1), 48 (2013); Takahashi, Y., et al.: Cardiovas. Diabetology, 10(1), 45 (2011);

• Marca: TRC

Propriedades químicas

• Peso molecular: 380.66
• Fórmula: C₈H₈Cl₃N₃O₄S₂
• Cor/forma: Neat
• InChI: InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
• Chave InChI: InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O