4-(Trifluoromethyl)benzyl Bromide

CAS: 402-49-3

Ref. TR-T790585

Informação sobre produto

• Nome: 4-(Trifluoromethyl)benzyl Bromide
• Sinónimos: alpha'-Bromo-alpha,alpha,alpha-trifluoro-p-xylene, 1-(Bromomethyl)-4-(trifluoromethyl)benzene, 1-Trifluoromethyl-4-(bromomethyl)benzene, 4-Bromomethylbenzotrifluoride, p-(Trifluoromethyl)benzyl bromide, alpha'-Bromo-alpha,alpha,alpha-trifluoro-p-xylene, 4-(Trifluoromethyl)Benzyl Bromide, 4-Trifluoromethylbenzyl Bromide, Benzene, 1-(bromomethyl)-4-(trifluoromethyl)-, p-Xylene, α′-bromo-α,α,α-trifluoro-, α′-Bromo-α,α,α-trifluoro-p-xylene

Descrição

Applications 4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Porcari, A., et al.: J. Med. Chem., 41, 1252 (1998); Ishida, T., et al.: Bioorg. Med. Chem. Lett., 16, 1859 (2006)

• Marca: TRC

Propriedades químicas

• Peso molecular: 239.03
• Fórmula: C₈H₆BrF₃
• Cor/forma: Neat
• InChI: InChI=1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2
• Chave InChI: InChIKey=IKSNDOVDVVPSMA-UHFFFAOYSA-N
• SMILES: FC(F)(F)c1ccc(CBr)cc1