(6a,11b,16a,17a)-(6'a,11'b,16'a,17'a)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one

CAS: 960071-64-1

Ref. TR-T886430

Informação sobre produto

• Nome: (6a,11b,16a,17a)-(6'a,11'b,16'a,17'a)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one
• Sinónimos: 17,17'-(trisulfanediyldicarbonyl)bis(6a,9-difluoro-11ß-hydroxy-16a-methyl-3-oxoandrosta-1,4-dien-17a-yl) dipropanoate, Fluticasone Propionate Imp. I (EP), (6alpha,11beta,16alpha,17alpha)-(6'alpha,11'beta,16'alpha,17'alpha)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one

Descrição

Impurity Fluticasone EP Impurity I
Applications Dimerized impurity of Fluticasone propionate (F599500), a antiallergic, anti-asthmatic and anti-inflammatory agent.
References Zheng, J., et al.: Org. Prep. Proced. Int., 40, 566 (2008); Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990); Mitchison, H.C., et al.: Gut, 32, 260 (1991); Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

• Marca: TRC

Propriedades químicas

• Peso molecular: 967.16
• Fórmula: C₄₈H₅₈F₄O₁₀S₃
• Cor/forma: Neat
• InChI: InChI=1S/C48H58F4O10S3/c1-9-37(57)61-47(23(3)15-27-29-19-33(49)31-17-25(53)11-13-41(31,5)45(29,51)35(55)21-43(27,47)7)39(59)63-65-64-40(60)48(62-38(58)10-2)24(4)16-28-30-20-34(50)32-18-26(54)12-14-42(32,6)46(30,52)36(56)22-44(28,48)8/h11-14,17-18,23-24,27-30,33-36,55-56H,9-10,15-16,19-22H2,1-8H3/t23-,24-,27+,28+,29+,30+,33+,34+,35+,36+,41+,42+,43+,44+,45+,46+,47+,48+/m1/s1
• Chave InChI: InChIKey=ZJXNXEBDTAODDP-RUXGNHTFSA-N
• SMILES: CCC(=O)O[C@]1(C(=O)SSSC(=O)[C@@]2(OC(=O)CC)[C@H](C)C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@@]32C)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C