(3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester

CAS: 157401-01-9

Ref. TR-T887910

Informação sobre produto

• Nome: (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester
• Marca: TRC
• Descrição: Applications (3α,5β,7α,12α)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid Ethyl Ester is an intermediate in the synthesis of (25R)-3β,7α,12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood.References Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000); Bjorkhem, I.: J. Clin. Invest., 6, 725(2002); Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)

Propriedades químicas

• Peso molecular: 476.35
• Fórmula: C₂₉H₄₈O₅
• Cor/forma: Neat
• InChI: InChI=1S/C29H48O5/c1-6-34-27(33)18(3)9-7-8-17(2)21-10-11-22-26-23(16-25(32)29(21,22)5)28(4)13-12-20(30)14-19(28)15-24(26)31/h9,17,19-26,30-32H,6-8,10-16H2,1-5H3/b18-9+/t17-,19+,20-,21-,22?,23?,24-,25+,26?,28+,29-/m1/s1
• Chave InChI: InChIKey=RWMGPYRVBGIPEW-IZYHOLNDSA-N
• SMILES: CCOC(=O)/C(C)=C/CC[C@@H](C)[C@H]1CCC2C3C(C[C@H](O)[C@@]21C)[C@@]1(C)CC[C@@H](O)C[C@H]1C[C@H]3O