(S)-1-((S)-2-(3,4,5-Trimethoxyphenyl)butanoyl)piperidine-2-carboxylic Acid

CAS: 195202-09-6

Ref. TR-T907590

Informação sobre produto

• Nome: (S)-1-((S)-2-(3,4,5-Trimethoxyphenyl)butanoyl)piperidine-2-carboxylic Acid
• Sinónimos: (2S)-1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylic Acid
• Marca: TRC

Descrição

Applications (S)-1-((S)-2-(3,4,5-Trimethoxyphenyl)butanoyl)piperidine-2-carboxylic Acid is an intermediate for the synthesis of dTAG-7 (D710015), which is a degradation tag, was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer research.
References Hai-Tsang Huang., eLife, 1-29, (2017)

Propriedades químicas

• Peso molecular: 365.42
• Fórmula: C₁₉H₂₇NO₆
• Cor/forma: Neat
• InChI: InChI=1S/C19H27NO6/c1-5-13(18(21)20-9-7-6-8-14(20)19(22)23)12-10-15(24-2)17(26-4)16(11-12)25-3/h10-11,13-14H,5-9H2,1-4H3,(H,22,23)/t13-,14-/m0/s1
• Chave InChI: InChIKey=QSLGUZZUFDIKSY-KBPBESRZSA-N
• SMILES: CC[C@H](C(=O)N1CCCC[C@H]1C(=O)O)c1cc(OC)c(OC)c(OC)c1