(+)-cis-Vincaminic Acid Ethyl-d5 Ester

CAS: 40163-56-2

Ref. TR-V314212

Informação sobre produto

• Nome: (+)-cis-Vincaminic Acid Ethyl-d5 Ester
• Sinónimos: 1,1,2,2,2-pentadeuterioethyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2(7),3,5,8(18)-tetraene-17-carboxylate, (+)-Ethyl vincaminate, (+)-cis-Vincaminic acid ethyl ester, 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic acid deriv., Eburnamenine-14-Carboxylic Acid, 14,15-Dihydro-14-Hydroxy-, Ethyl Ester, (3A,14B,16A)-, Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, ethyl ester, (3-α,14-β,16-α)-, Ethyl (+)-cis-vincaminate, Vincaminic acid ethyl ester
• CAS: 40163-56-2

Descrição

Applications (+)-cis-Vincaminic Acid Ethyl-d5 Ester is labelled (+)-cis-Vincaminic Acid Ethyl Ester (V314210) which is a derivative of Vinpocetine (D448350). It has been shown that under stressed conditions, vinpocetine equilibrates with Vincaminic Acid Ethyl Ester and hydrolyzes to Apovincaminic Acid (A729250).
References Muhammad, N., et al.: J. Pharmaceu. Sci., 77, 126 (1988); Han, et al.: J. Biol. Chem., 274, 22337 (1999), O’Donnell, et al.: Pharmacol. Biochem. Behav., 63, 185 (1999);

• Marca: TRC

Propriedades químicas

• Peso molecular: 373.5
• Fórmula: C₂₂D₅H₂₃N₂O₃
• Cor/forma: Neat
• InChI: InChI=1S/C22H28N2O3/c1-3-21-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(18(16)19(21)23)22(26,14-21)20(25)27-4-2/h5-6,8-9,19,26H,3-4,7,10-14H2,1-2H3/t19-,21+,22+/m1/s1/i2D3,4D2
• Chave InChI: InChIKey=XRMLLVHAALNSGZ-RITWPEFUSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])OC(=O)[C@@]1(O)C[C@]2(CC)CCCN3CCc4c(n1c1ccccc41)[C@@H]32