Vadadustat

CAS: 1000025-07-9

Ref. TR-V849530

Informação sobre produto

• Nome: Vadadustat
• Sinónimos: Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-, N-[[5-(3-Chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]glycine, 2-[[[5-(3-Chlorophenyl)-3-hydroxypyridin-2-yl]carbonyl]amino]acetic acid, AKB 6548, PG 1016548
• Marca: TRC

Descrição

Applications Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.
References Pergola, P., et al.: Kidney Int., 90, 1115 (2016);

Propriedades químicas

• Peso molecular: 306.7
• Fórmula: C₁₄H₁₁ClN₂O₄
• Cor/forma: Neat
• InChI: InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)
• Chave InChI: InChIKey=JGRXMPYUTJLTKT-UHFFFAOYSA-N
• SMILES: O=C(O)CNC(=O)c1ncc(-c2cccc(Cl)c2)cc1O