Zibotentan

CAS: 186497-07-4

Ref. TR-Z359900

Informação sobre produto

• Nome: Zibotentan
• Sinónimos: N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]-3-pyridinesulfonamide, N-(3-Methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3sulfonamide, ZD 4054, 3-Pyridinesulfonamide, N-(3-methoxy-5-methyl-2-pyrazinyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]-, 3-Pyridinesulfonamide, N-(3-methoxy-5-methylpyrazinyl)-2-(4-(1,3,4-oxadiazol-2-yl)phenyl)-, Zd 4054, Zd4054
• CAS: 186497-07-4

Descrição

Applications Zibotentan is a specific endothelin-A receptor antagonist that is a potential candidate in the treatment of prostate cancer, bone metastasis and various other types of cancer.
References Carducci, M., Jimeno, A.: Clin. Cancer Res., 12, 6296s (2006); James, N., et al.: Eur Urol., 55, 1112 (2009);

• Marca: TRC

Propriedades químicas

• Peso molecular: 424.43
• Fórmula: C₁₉H₁₆N₆O₄S
• Cor/forma: Neat
• InChI: InChI=1S/C19H16N6O4S/c1-12-10-21-17(19(23-12)28-2)25-30(26,27)15-4-3-9-20-16(15)13-5-7-14(8-6-13)18-24-22-11-29-18/h3-11H,1-2H3,(H,21,25)
• Chave InChI: InChIKey=FJHHZXWJVIEFGJ-UHFFFAOYSA-N
• SMILES: COc1nc(C)c[nH]c1=NS(=O)(=O)c1cccnc1-c1ccc(-c2nnco2)cc1