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VUN 00829
CAS:VUN 00829, a Cy5 labeled PEG with a reactive carboxyl end, enhances solubility and is trackable by its fluorescence.Fórmula:C45H65ClN2O10Cor e Forma:SolidPeso molecular:829.47SKOG102
CAS:SKOG102, a potent OLIG2 inhibitor, blocks DNA binding for GBM research.Fórmula:C19H25Cl2N7Cor e Forma:SolidPeso molecular:422.35Dihydronarwedine
CAS:Dihydronarwedine is a metabolite of Galanthamine, an inhibitor of glycogen synthase kinase 3β (GSK3β)Fórmula:C17H21NO3Cor e Forma:SolidPeso molecular:287.35Iferanserin HCl
CAS:Iferanserin HCl is a selective serotonin receptor antagonist.Fórmula:C23H29ClN2OCor e Forma:SolidPeso molecular:384.95PEAQX sodium
CAS:<p>PEAQX (NVP-AAM077) is a competitive NMDA antagonist, mildly prefers GluN1/GluN2A to GluN2B, and acts as an anticonvulsant.</p>Fórmula:C17H15BrN3Na4O6PCor e Forma:SolidPeso molecular:560.1588EML-405
CAS:<p>EML-405 is a small-molecule inhibitor of SPIN1 ( Kd of 14 uM).</p>Fórmula:C36H51N5O2Cor e Forma:SolidPeso molecular:585.82Pidnarulex HCl
CAS:Pidnarulex HCl is CX-5461, a selective Pol I inhibitor and p53 activator without DNA damage, showing potent anti-cancer efficacy.Fórmula:C27H28ClN7O2SCor e Forma:SolidPeso molecular:550.08CAM4066
CAS:CAM4066 is a novel potent and selective CK2alpha inhibitor.Fórmula:C26H26ClN3O4Cor e Forma:SolidPeso molecular:479.96SNAP8 Acetate(868844-74-0,free base)
Diminishing the appearance of wrinkles.Fórmula:C43H74N16O18SPureza:99.45%Cor e Forma:SolidPeso molecular:1135.21Nitroprusside disodium dihydrate
CAS:<p>Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.</p>Fórmula:C5H4FeN6Na2O3Pureza:98%Cor e Forma:Bright RedPeso molecular:297.95EML631
CAS:EML631 is a potent and selective SPIN1 inhibitor (SPIN1 Kd= 3 microM).Fórmula:C41H60N6O3Cor e Forma:SolidPeso molecular:684.95CU-6PMN
CAS:CU-6PM, a fluorescent RXR agonist, allows easy rexinoid screening via fluorescence changes in microplate readers.Fórmula:C25H26O5Cor e Forma:SolidPeso molecular:406.47AS2541019
CAS:AS2541019 is a selective Phosphatidylinositol-3-kinase p110δ (PI3Kδ) inhibitor.Fórmula:C26H33F2N7O3Cor e Forma:SolidPeso molecular:529.58Lenumlostat
CAS:<p>Lenumlostat is a lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.</p>Fórmula:C18H17F4N3O3Pureza:99.11%Cor e Forma:SolidPeso molecular:399.34Variegatic acid
CAS:Variegatic acid inhibits β-hexosaminidase, TNF-α (IC50: 10.4, 16.8μM), and PKC β1 (IC50: 36.2μM) in RBL 2H3 cells.Fórmula:C18H12O9Cor e Forma:SolidPeso molecular:372.28GX-585
CAS:<p>GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.</p>Fórmula:C24H25Cl2FN4O3SPureza:99.02% - 99.03%Cor e Forma:SolidPeso molecular:539.45MDK3673
CAS:MDK3673, also known as Olfr895-Agonist-10, is a novel specific agonist of odorant receptor 895 (Olfr895).Fórmula:C14H17NO4Cor e Forma:SolidPeso molecular:263.29EphB1-IN-10
CAS:EphB1-IN-10 is a potent and selective covalent inhibitor of receptor tyrosine kinase EphB1.Fórmula:C17H15ClN4O2Cor e Forma:SolidPeso molecular:342.78Adriforant tartrate hydrate
CAS:<p>Adriforant (ZPL-3893787), a promising H4 receptor antagonist, may treat allergic diseases.</p>Fórmula:C17H32N6O8Cor e Forma:SolidPeso molecular:448.48Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Fórmula:C16H25N7O8Cor e Forma:SolidPeso molecular:443.41Sulfadiazine sodium
CAS:<p>Sulfadiazine sodium (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.</p>Fórmula:C10H10N4O2S·NaPureza:99.75%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:272.26SAS-0132
CAS:SAS-0132 is a modulator/antagonist of sigma2R/TMEM97 and has potential for treating TBIs, Alzheimer's disease, and neuropathic pain.Fórmula:C24H29N3O2Cor e Forma:SolidPeso molecular:391.51BRF110
CAS:BRF110: brain-penetrant Nurr1:RXRα agonist, neuroprotective against PD, boosts dopamine, no dyskinesia in mice.Fórmula:C22H18F3N3O2Cor e Forma:SolidPeso molecular:413.39EPZ020411 HCl
CAS:EPZ020411: potent, selective PRMT6 inhibitor, good bioavailability in rats, enhances radiotherapy in GSC brain tumors.Fórmula:C25H40Cl2N4O3Cor e Forma:SolidPeso molecular:515.52Brigimadlin
CAS:Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.Fórmula:C31H25Cl2FN4O3Pureza:98.17%Cor e Forma:SolidPeso molecular:591.46PSMA-1007
CAS:PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.Fórmula:C49H55FN8O16Cor e Forma:SolidPeso molecular:1030.01NVR3-778 hydrate
CAS:<p>NVR 3-778: First CAM to show antiviral effects in HBV; 0.40 µM EC50; works across HBV genotypes, no cross-resistance with nucleoside inhibitors.</p>Fórmula:C18H18F4N2O5SCor e Forma:SolidPeso molecular:450.4APHS
CAS:APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.Fórmula:C15H18O2SCor e Forma:SolidPeso molecular:262.37Fiduxosin hydrochloride
CAS:<p>Fiduxosin hydrochloride is an alpha 1a-adrenoceptor antagonist that may be useful in the treatment of Benign Prostatic Hyperplasia.</p>Fórmula:C30H30ClN5O4SCor e Forma:SolidPeso molecular:592.11NAcM-COV
CAS:NAcM-COV is a specific, irreversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 28 nM.Fórmula:C28H35F3N4O2Cor e Forma:SolidPeso molecular:516.6Dichloro-all-trans-retinone
CAS:<p>Dichloro-all-trans-retinone is a selective inhibitor for retinaldehyde dehydrogenase enzymes, thereby irreversibly inhibiting RALDH1, 2, and 3.</p>Fórmula:C21H28Cl2OCor e Forma:SolidPeso molecular:367.35Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Fórmula:C26H44NNaO6SPureza:97.90%Cor e Forma:SolidPeso molecular:521.69LEO 134310
CAS:LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.Fórmula:C34H40N2O8Cor e Forma:SolidPeso molecular:604.69MFH290
CAS:MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.Fórmula:C26H31N5O3S2Cor e Forma:SolidPeso molecular:525.69OAT-1441
CAS:<p>OAT-1441 is a hAMCase inhibitor.</p>Fórmula:C23H27ClN6OCor e Forma:SolidPeso molecular:438.95VA4 TG2 inhibitor
CAS:VA4 is a novel irreversible TG2 transamidase site-specific inhibitor.Fórmula:C33H41N5O6SCor e Forma:SolidPeso molecular:635.77Etoloxamine HCl
CAS:Etoloxamine HCl is the salt form of Etoloxamine free base, a histamine 1 receptor antagonist.Fórmula:C19H26ClNOCor e Forma:SolidPeso molecular:319.87L0909
CAS:<p>L0909: Oral Hepatitis C inhibitor, novel action, EC50=0.022 μM, SI>600, blocks replication, effective against resistant strains.</p>Fórmula:C23H30ClN5Cor e Forma:SolidPeso molecular:411.97NK314
CAS:NK314, a benzo[c]phenanthridine, inhibits topoisomerase II causing DNA breaks within 1h, even without proteinase K digestion.Fórmula:C22H20ClNO4Cor e Forma:SolidPeso molecular:397.85INCB059872 tosylate
CAS:INCB059872: potent, selective oral LSD1 inhibitor, increasing tumor-suppressor gene expression by promoting H3K4 and H3K9 methylation.Fórmula:C37H50N2O9S2Cor e Forma:SolidPeso molecular:730.932Befiradol fumarate
CAS:Befiradol fumarate: potent 5-HT1A agonist for Parkinson's drug-induced dyskinesia.Fórmula:C24H26ClF2N3O5Cor e Forma:SolidPeso molecular:509.93Hexamethonium tartrate
CAS:Hexamethonium tartrate, a non-absorbable, brain-impenetrable ganglionic blocker, once used for hypertension, now a research tool.Fórmula:C20H38N2O122Cor e Forma:SolidPeso molecular:498.53SR12813
CAS:SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Fórmula:C24H42O7P2Pureza:99.43%Cor e Forma:SolidPeso molecular:504.53NCD38
CAS:NCD38 is a potent, selective LSD1 inhibitor.Fórmula:C37H37ClF3N3O4Pureza:98.21% - 98.86%Cor e Forma:SolidPeso molecular:680.16CMX-521
CAS:CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.Fórmula:C13H17N5O5Pureza:99.57%Cor e Forma:SolidPeso molecular:323.3CN-716 HCl
CAS:cn-716 is a novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor.Fórmula:C22H33BCl2N6O4Cor e Forma:SolidPeso molecular:527.25Citalopram oxalate
CAS:Citalopram oxalate: a serotonin uptake inhibitor, treats depression, lessens alcohol intake, favored for tardive dyskinesia over tricyclics.Fórmula:C22H23FN2O5Cor e Forma:SolidPeso molecular:414.43NLG802 HCl
CAS:NLG802, an oral indoximod prodrug, inhibits IDO enzyme, modulates immune response, and has anti-cancer properties.Fórmula:C18H26ClN3O3Cor e Forma:SolidPeso molecular:367.874MPT0L145
CAS:<p>MPT0L145 is a first-in-class PIK3C3/FGFR inhibitor.</p>Fórmula:C25H29Cl3N8O3Cor e Forma:SolidPeso molecular:595.91Ronopterin
CAS:Ronopterin is a potent Nitric oxide synthase inhibitor and Neuroprotectant.Fórmula:C9H16N6O2Cor e Forma:SolidPeso molecular:240.26PF-06862309
CAS:PF-06862309 is a PI3K inhibitorFórmula:C20H26F3N8O7PCor e Forma:SolidPeso molecular:578.44CGP-78608
CAS:CGP-78608 is a glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.Fórmula:C11H13BrN3O5PCor e Forma:SolidPeso molecular:378.12Ochromycinone
CAS:<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Fórmula:C19H14O4Pureza:99.21%Cor e Forma:SolidPeso molecular:306.31Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Fórmula:C18H24N6O2Cor e Forma:SolidPeso molecular:356.43BiBET
CAS:BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.Fórmula:C26H30N10O3Cor e Forma:SolidPeso molecular:530.58MK-8666 Tris
CAS:<p>MK-8666, a partial GPCR agonist, targets GPR40 to enhance insulin secretion, potentially treating type 2 diabetes without adverse effects.</p>Fórmula:C33H42N2O9SCor e Forma:SolidPeso molecular:642.764Fasoracetam monohydrate
CAS:Fasoracetam monohydrate: synthetic, activates glutamate receptors, trialed in Phases I-III for vascular dementia.Fórmula:C11H21N3O5Cor e Forma:SolidPeso molecular:275.31JPI-547 HCl
CAS:JPI-547 (NOV 1402) is an oral anti-cancer drug targeting PARP 1/2 and Tankyrase 1/2, effective alone or with chemo and immunotherapies.Fórmula:C23H26Cl2N6OCor e Forma:SolidPeso molecular:473.402KR30031
CAS:KR30031 is a novel verapamil-like P-glycoprotein inhibitor with fewer heart side-effects, potentially boosting paclitaxel's efficacy.Fórmula:C26H34N2O4Cor e Forma:SolidPeso molecular:438.56Quoromycin
CAS:Quoromycin, a new antivirulence drug, hinders Vibrio vulnificus by disrupting SmcR in quorum-sensing, reducing virulence in vitro and in vivo.Fórmula:C12H8N2O2SCor e Forma:SolidPeso molecular:244.27Tofacitinib maleate
CAS:<p>Tofacitinib (tasocitinib, CP-690550) is a JAK inhibitor blocking cytokine signaling and STAT activation.</p>Fórmula:C16H20N6O·xC4H4O4Cor e Forma:SolidPeso molecular:428.449NAS-181 free base
CAS:NAS-181 free base is a 5-HT(1B) receptor antagonist.Fórmula:C19H26N2O4Cor e Forma:SolidPeso molecular:346.42SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Cor e Forma:Yellow-Green SolidPeso molecular:296.32CJ-15161 hydrochloride
CAS:CJ-15161 hydrochloride is the salt form of CJ-15161 (free base), an opioid κ-receptor agonist, is undergoing development with Pfizer as an analgesic agent.Fórmula:C23H32ClN3O2Cor e Forma:SolidPeso molecular:417.978CJ-15161 (free base)
CAS:<p>CJ-15161 (free base), an opioid κ-receptor agonist, is undergoing development with Pfizer as an analgesic agent.</p>Fórmula:C23H31N3O2Cor e Forma:SolidPeso molecular:381.51IDN-1965
CAS:IDN-1965: potent, irreversible caspase inhibitor; blocks Fas-induced apoptosis; varied administration; promising for liver injury treatment.Fórmula:C21H26FN3O5Cor e Forma:SolidPeso molecular:419.45Bornaprine
CAS:Bornaprine is an anticholinergic drug used to treat Parkinson's disease due to inhibition of muscarinic or nicotinic transmission.Fórmula:C21H31NO2Cor e Forma:SolidPeso molecular:329.48TP1287
CAS:TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.Fórmula:C21H21ClNO8PCor e Forma:SolidPeso molecular:481.82Laropiprant analog
CAS:Laropiprant analog is an antagonist of the prostaglandin PGD2 receptor DP1.Fórmula:C20H18ClFN2O4SCor e Forma:SolidPeso molecular:436.88ML416
CAS:<p>ML416 is an inhibitor of HIV-1.</p>Fórmula:C14H15FN2OS2Cor e Forma:SolidPeso molecular:310.41RWJ-60475
CAS:RWJ-60475 is a novel CD45 phosphatase inhibitor.Fórmula:C13H11BrNO7PCor e Forma:SolidPeso molecular:404.11SU6656
CAS:SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.Fórmula:C19H21N3O3SPureza:98.21% - 98.73%Cor e Forma:SolidPeso molecular:371.45AZD5718
CAS:AZD5718: potent FLAP inhibitor (IC50=2.0 nM), treats Coronary Artery Disease, >90% leukotriene suppression, safe in animal studies, in phase 2a trial.Fórmula:C29H34N6O4Cor e Forma:SolidPeso molecular:530.62GNF7156
CAS:GNF7156 is a potent and selective DYRK1A inhibitor.Fórmula:C22H22N6O3Cor e Forma:SolidPeso molecular:418.45ONL-1204
CAS:ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Fórmula:C71H100N18O16Cor e Forma:SolidPeso molecular:1461.66PF-04363467 HCl
CAS:<p>PF-04363467 HCl is a selective dopamine D3/D2 receptor antagonist.</p>Fórmula:C22H30N2O3SCor e Forma:SolidPeso molecular:402.55Phenamil
CAS:Phenamil is an inhibitor of epithelial sodium channels, activates the osteomorphin protein pathway to promote bone repair and induces significant fat formation.Fórmula:C12H12ClN7OPureza:99.07%Cor e Forma:SolidPeso molecular:305.72Istaroxime oxalate
CAS:<p>Istaroxime (PST-2744) is a positive inotrope that inhibits Na+/K+ ATPase, raising intracellular sodium and calcium levels.</p>Fórmula:C23H34N2O7Cor e Forma:SolidPeso molecular:450.53WS-691
CAS:<p>WS-691: potent oral ABCB1 modulator; lowers PTX IC50 to 22.02 nM in SW620/Ad300 cells; raises [3H]-PTX uptake; non-toxic in vivo.</p>Fórmula:C20H16FN7SCor e Forma:SolidPeso molecular:405.45BC-1485
CAS:<p>BC-1485 is a small molecule inhibitor of FIEL1 that inhibits the degradation of PIAS4 and ameliorates fibrosis in a mouse model.</p>Fórmula:C19H21N5O5SPureza:97.03% - 97.15%Cor e Forma:SolidPeso molecular:431.47Brostallicin HCl
CAS:Brostallicin, a synthetic MGB, inhibits DNA replication in cancer cells, inducing cell death, effective against MMR-defective tumors.Fórmula:C30H36BrClN12O5Cor e Forma:SolidPeso molecular:760.04Risvodetinib
CAS:Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.Fórmula:C33H34N8O2Cor e Forma:SolidPeso molecular:574.68Tedizolid Phosphate
CAS:Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.Fórmula:C17H16FN6O6PPureza:97.96%Cor e Forma:SolidPeso molecular:450.32XMU-MP-2
CAS:<p>XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft</p>Fórmula:C32H33F3N8O2Pureza:99.29%Cor e Forma:SolidPeso molecular:618.65CRM-51005
CAS:<p>CRM-51005 is a new phospholipase C inhibitor produced by unidentified fungal strain MT51005</p>Fórmula:C15H20O3Cor e Forma:SolidPeso molecular:248.32VPC-16606
CAS:VPC-16606 inhibits ERα cell growth & gene expression, blocking ERα-LBD & SRC-3 binding dose-dependently.Fórmula:C17H13ClN2O2SCor e Forma:SolidPeso molecular:344.82Ixazomib citrate EtOH
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib, is an oral, next-gen proteasome inhibitor with enhanced anti-cancer properties.Fórmula:C22H29BCl2N2O10Cor e Forma:SolidPeso molecular:563.188Ticalopride
CAS:Ticalopride: 5-HT3 agonist for digestive, orofacial, ENT disorders, and bulimia, GERD, IBS research.Fórmula:C14H20ClN3O3Pureza:99.51%Cor e Forma:SolidPeso molecular:313.78Lifirafenib HCl
CAS:Lifirafenib (Beigene-283/BGB-283): a potent, selective RAF/EGFR inhibitor effective against B-RAF mutated colorectal cancers.Fórmula:C26H19ClF3N3O3Cor e Forma:SolidPeso molecular:513.9012BMS-955176 HCl
CAS:<p>GSK-3532795: a broader-spectrum HIV-1 maturation inhibitor than bevirimat, effective in vitro and clinically.</p>Fórmula:C42H62N2O4SCor e Forma:SolidPeso molecular:727.486AMG2504
CAS:AMG2504 is a TRPA1 inhibitor.Fórmula:C15H10Cl4N2O3SCor e Forma:SolidPeso molecular:440.13Metitepine
CAS:Metitepine is a serotonin receptor antagonist in the CNS used as an antipsychotic.Fórmula:C20H24N2S2Cor e Forma:SolidPeso molecular:356.55(S)-Pomalidomide
CAS:(S)-Pomalidomide is an inhibitor of angiogenesis and growth of B-cell neoplasias, which induces complete regressions of Burkitt's lymphoma cell tumors.Fórmula:C13H11N3O4Cor e Forma:SolidPeso molecular:273.24Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Fórmula:C22H30N6OSBrHPureza:97.83% - 99.92%Cor e Forma:SolidPeso molecular:628.86Ruboxistaurin mesylate monohydrate
CAS:<p>Ruboxistaurin mesylate monohydrate, a PKC beta inhibitor, may treat diabetic nephropathy and macular edema, reducing oxidative stress and neovascularization.</p>Fórmula:C29H34N4O7SCor e Forma:SolidPeso molecular:582.67Difenamizole HCl
CAS:Difenamizole HCl, a pyrazolone NSAID with analgesic effects, modulates dopamine and inhibits monoamine oxidase.Fórmula:C20H23ClN4OCor e Forma:SolidPeso molecular:370.88Glutathione sodium
CAS:<p>Glutathione sodium, a water-soluble form of PAO, blocks blood vessel formation and cancer growth.</p>Fórmula:C10H16N3NaO6SCor e Forma:SolidPeso molecular:329.3BIM-46068
CAS:<p>BIM-46068 is a potent inhibitor of human farnesyltransferase with a unique anti-proliferative profile.</p>Fórmula:C21H42N4O3S3Cor e Forma:SolidPeso molecular:494.78BIM-46050
CAS:BIM-46050: potent human farnesyltransferase inhibitor, free acid of BIM-46068, nanomolar IC50, highly selective over GGTase.Fórmula:C20H40N4O3S3Cor e Forma:SolidPeso molecular:480.75
