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Termina em 31 de dez.( faltam 11 dias )
AJ-3941
CAS:<p>AJ-3941: Selective calcium channel blocker, prevents lipid peroxidation, potential for treating brain vessel disorders.</p>Fórmula:C35H35FN2O9Cor e Forma:SolidPeso molecular:646.67NA 382
CAS:<p>NA 382 is a staurosporine derivative that inhibits multidrug resistance.</p>Fórmula:C31H28N4O6Cor e Forma:SolidPeso molecular:552.58DHPM-93
CAS:<p>DHPM-93 is a the most potent inhibitor of sodium iodide symporter (nis) reported to date</p>Fórmula:C18H18N2O5Cor e Forma:SolidPeso molecular:342.35CCG-203586
CAS:<p>CCG-203586 is a novel potent glucosylceramide synthase (GCS) inhibitor.</p>Fórmula:C26H32N2O4Cor e Forma:SolidPeso molecular:436.54HJC-0123
CAS:<p>HJC-0123: inhibits STAT3, boosts cleaved caspase-3, hinders cell growth, triggers apoptosis, effective in ER-negative breast/pancreatic cancer.</p>Fórmula:C24H16N2O3SCor e Forma:SolidPeso molecular:412.46UNC1666
CAS:<p>UNC1666 is a dual ATP-competitive small molecule tyrosine kinase inhibitor, which potently diminishes Mer and Flt3 phosphorylation in AML.</p>Fórmula:C26H35N5O4SCor e Forma:SolidPeso molecular:513.65S 0960
CAS:<p>S 0960 is a dimeric bile acid analogue, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.</p>Fórmula:C48H79NO8Pureza:99.32% - >99.99%Cor e Forma:SolidPeso molecular:798.14MEN-10354
CAS:<p>MEN-10354 is a less potent and less selective NK-2 tachykinin receptor antagonist compared to the linear analog, R 396.</p>Fórmula:C37H46N8O9Cor e Forma:SolidPeso molecular:746.81UAWJ246
CAS:<p>UAWJ246 is a SARS-CoV-2 Protease inhibitor (IC50 = 45 nM). UAWJ246 provides new directions for the development of Mpro inhibitors as SARS-CoV-2 antivirals.</p>Fórmula:C25H34N4O6Cor e Forma:SolidPeso molecular:486.56ITP-2
CAS:<p>ITP-2 activates hERG channels, shifts inactivation midpoint depolarization, and activation voltage hyperpolarization.</p>Fórmula:C19H14F3N5O2Cor e Forma:SolidPeso molecular:401.34ST7612AA1
CAS:<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Fórmula:C20H27N3O4SPureza:99.71%Cor e Forma:SolidPeso molecular:405.51MRT-92 HCl salt
CAS:<p>MRT-92 is a potent Smoothened receptor inhibitor with an IC50 of 0.4 nM, affecting Hh pathway and cancer drug target.</p>Fórmula:C33H35ClN4O5Cor e Forma:SolidPeso molecular:603.12HA-29
CAS:<p>HA-29 is an inhibitor of thromboxane A2 and prostaglandin endoperoxide receptors.</p>Fórmula:C16H16N2O3Cor e Forma:SolidPeso molecular:284.31CP 100356
CAS:<p>CP 100356: Specific MDR1 (P-Gp) inhibitor with low uM/nM potency against MDR-1 substrates in MDCKII cells.</p>Fórmula:C31H36N4O6Cor e Forma:SolidPeso molecular:560.64Erythromycin hydrochloride
CAS:<p>Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.</p>Fórmula:C37H68ClNO13Cor e Forma:SolidPeso molecular:770.39(+)-Donepezil
CAS:<p>(+)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.</p>Fórmula:C24H29NO3Cor e Forma:SolidPeso molecular:379.49MDL-100173
CAS:<p>MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor.</p>Fórmula:C24H26N2O4SCor e Forma:SolidPeso molecular:438.54SAR296968
CAS:<p>SAR296968 is a novel selective NCX inhibitor, improving cardiac function and restoring sympathovagal balance in heart failure.</p>Fórmula:C22H22N2O4SCor e Forma:SolidPeso molecular:410.49Nomifensine maleate
CAS:<p>Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.</p>Fórmula:C20H22N2O4Pureza:98.46%Cor e Forma:SolidPeso molecular:354.4Calanolide B
CAS:<p>Calanolide B is one of a novel class of HIV-inhibiting coumarins from the tropical rainforest tree, Calophyllum lanigerum.</p>Fórmula:C22H26O5Cor e Forma:SolidPeso molecular:370.44CHDI340246
CAS:<p>CHDI-340246 is a potent and selective kynurenine mono-oxygenase (KMO) inhibitor.</p>Fórmula:C14H11ClN2O3Cor e Forma:SolidPeso molecular:290.7JQ1-Acid HCl
CAS:<p>(+)-JQ-1 carboxylic acid: potent BET inhibitor, precursor for PROTACs synthesis.</p>Fórmula:C19H18Cl2N4O2SCor e Forma:SolidPeso molecular:437.339DK-139
CAS:<p>DK-139 is an inhibitor of NF-kappaB-mediated GROalpha expression, suppressing the TNFalpha-induced invasive capability of MDA-MB-231 human breast cancer cells.</p>Fórmula:C18H18O5Cor e Forma:SolidPeso molecular:314.33RB-005
CAS:<p>RB-005 is a potent SK1 inhibitor with IC(50) of 3.6 μM, potentially treating proliferative diseases like hypertension and degrades SK1 in human cells.</p>Fórmula:C21H35NOCor e Forma:SolidPeso molecular:317.51SA 152
CAS:<p>SA 152 is an organophosphoric inhibitor.</p>Fórmula:C19H12F12NO2PCor e Forma:SolidPeso molecular:545.26APTO-253 isomer
CAS:<p>APTO-253 isomer, a variant with a Fluoro-atom at the 6-position, inhibits MTF-1, inducing KLF4 and blocking cell cycle progression.</p>Fórmula:C22H14FN5Cor e Forma:SolidPeso molecular:367.38Paullone
CAS:<p>Paullone is an inhibitor of cyclin-dependent kinases (CDKs). The CDKs are a family of protein kinases that are involved in regulation of the cell cycle.</p>Fórmula:C16H12N2OCor e Forma:SolidPeso molecular:248.28U 92032
CAS:<p>U 92032 is a T-channel antagonist and antioxidant that inhibits lipid peroxidation.</p>Fórmula:C30H35F2N3O2Cor e Forma:SolidPeso molecular:507.61FCE-27262
CAS:<p>FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.</p>Fórmula:C23H31N3O3Cor e Forma:SolidPeso molecular:397.51Oxyphenisatine
CAS:<p>Oxyphenisatine, a laxative with anticancer properties, may cause liver damage over time.</p>Fórmula:C20H15NO3Pureza:97.35%Cor e Forma:SolidPeso molecular:317.34M2WJ332
CAS:<p>M2WJ332 is a novel M2-S31N inhibitor, showing antiviral activity against Influenza A virus.</p>Fórmula:C18H22N2OSCor e Forma:SolidPeso molecular:314.45AZD-3839 hemifumarate
CAS:<p>AZD-3839 hemifumarate is a potent and selective BACE1 inhibitor and clinical candidate for the treatment of Alzheimer's disease.</p>Fórmula:C52H36F6N10O4Cor e Forma:SolidPeso molecular:978.92PF-06412154 HCl
CAS:<p>PF-06412154 HCl is a glucagon receptor antagonist.</p>Fórmula:C24H28ClN3O3Cor e Forma:SolidPeso molecular:441.96BW-10
CAS:<p>BW-10 potently inhibits bombesin evoked release of gastrointestinal hormones in vitro and in vivo.</p>Fórmula:C57H72N14O8Cor e Forma:SolidPeso molecular:1081.27(-)-Donepezil
CAS:<p>(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase.</p>Fórmula:C24H29NO3Cor e Forma:SolidPeso molecular:379.49AQW-051 fumarate
CAS:<p>AQW-051 fumarate is an α7 nicotinic ACh receptor partial agonist that may act as a cognitive-enhancing agent.</p>Fórmula:C23H26N2O5Cor e Forma:SolidPeso molecular:410.47ArgTX-48 TFA
CAS:<p>ArgTX-48 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.</p>Fórmula:C40H62F9N11O14Cor e Forma:SolidPeso molecular:1091.9846KNI 174
CAS:<p>KNI 174 is a new type of anti‐AIDS drug used as an HIV‐1 protease inhibitor</p>Fórmula:C36H45N5O7SCor e Forma:SolidPeso molecular:691.84CR-6086
CAS:<p>CR6086: potent EP4 antagonist with DMARD effects, low Ki (16.6 nM), and specific anti-inflammatory action.</p>Fórmula:C26H27F3N2O3Cor e Forma:SolidPeso molecular:472.5MLAF50
CAS:<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Fórmula:C15H12I2O4Cor e Forma:SolidPeso molecular:510.06Pitavastatin
CAS:<p>Pitavastatin (NK-104) is an HMG-CoA reductase inhibitor with hypocholesterolemic and neuroprotective activities.</p>Fórmula:C25H24FNO4Pureza:97.17%Cor e Forma:SolidPeso molecular:421.46CD08108
CAS:<p>CD08108 is a MC1R agonist.</p>Fórmula:C31H38N4O4Cor e Forma:SolidPeso molecular:530.66UU-T01
CAS:<p>UU-T01 inhibits β-catenin/Tcf4 with Ki of 3.14 µM, binds β-catenin directly with KD of 0.531 µM.</p>Fórmula:C10H10N6OCor e Forma:SolidPeso molecular:230.23N 0861
CAS:<p>N 0861 is a selective adenosine A1 receptor antagonist that attenuates renal insufficiency during adenosine-controlled hypotension in rats.</p>Fórmula:C13H17N5Pureza:98.78%Cor e Forma:SolidPeso molecular:243.31NNC 0772
CAS:<p>NNC 0772 is a dopamine D-1 receptor antagonist</p>Fórmula:C19H21Cl2NO2Cor e Forma:SolidPeso molecular:366.28GSK-2256098 HCl
CAS:<p>GSK-2256098 HCl is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.</p>Fórmula:C20H24Cl2N6O2Cor e Forma:SolidPeso molecular:451.35Motuporin
CAS:<p>Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).</p>Fórmula:C40H57N5O10Cor e Forma:SolidPeso molecular:767.91RO2443
CAS:<p>RO2443 is a dual inhibitor of the MDM2-p53 or MDMX-p53 protein-protein interaction, inducung MDM2 and MDMX dimerization and activating the p53 pathway.</p>Fórmula:C20H14ClF2N3O2Cor e Forma:SolidPeso molecular:401.79BQ-610
CAS:<p>BQ-610 is an Endothelin A receptor antagonist.</p>Fórmula:C36H44N6O6Cor e Forma:SolidPeso molecular:656.77Vadaclidine
CAS:<p>Vadaclidine is an orally acting antinociceptive muscarinic agonist.</p>Fórmula:C13H21N3S2Cor e Forma:SolidPeso molecular:283.46
