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Termina em 31 de dez.( faltam 11 dias )
PM-43I
CAS:<p>PM-43I is a potent inhibitor of both STAT5- and STAT6-dependent allergic airway disease in mice.</p>Fórmula:C38H50F2N3O10PCor e Forma:SolidPeso molecular:777.79SRI-31277
CAS:SRI-31277 is a TSP1-TGFβ inhibitor.Fórmula:C17H33N5O5Cor e Forma:SolidPeso molecular:387.47Cangrelor free acid
CAS:<p>Cangrelor, a reversible P2Y12 inhibitor for IV use, was approved in June 2015; it rapidly blocks ADP-induced platelet aggregation.</p>Fórmula:C17H25Cl2F3N5O12P3S2Cor e Forma:SolidPeso molecular:776.36PNR-7-02
CAS:<p>PNR-7-02 is an inhibitor of human DNA polymerase eta (Polη).</p>Fórmula:C24H16ClN3O2SCor e Forma:SolidPeso molecular:445.92Lu AF58786
CAS:<p>Lu AF58786 inhibits LRRK2, and variants G2019S & A2016T56, with IC50: 12, 19, and 93 nM.</p>Fórmula:C19H16N6Cor e Forma:SolidPeso molecular:328.37VU0487836
CAS:<p>VU0487836 is a cyclooxygenase-1 (COX-1)-selective inhibitor.</p>Fórmula:C17H13FO3Cor e Forma:SolidPeso molecular:284.281-IODOADAMANTANE
CAS:<p>1-IODOADAMANTANE (1-Adamantyl Iodide) is employed in the free-radical carbonylation reactions with alkenes.</p>Fórmula:C10H15IPureza:99.799% - 99.95%Cor e Forma:SolidPeso molecular:262.13JHU-58
CAS:<p>JHU-58: new MrgC agonist reducing pain and sensory hypersensitivity post-nerve injury in rats/mice, ineffective in Mrg knockout mice.</p>Fórmula:C19H24N6O2Cor e Forma:SolidPeso molecular:368.43D-473
CAS:<p>D-473 is a novel orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.</p>Fórmula:C26H27F2NO3Cor e Forma:SolidPeso molecular:439.49MRS542
CAS:<p>MRS542 acts as an A3AR antagonist and partial agonist; its partial agonism is due to LUF6000.</p>Fórmula:C17H17ClIN5O4Cor e Forma:SolidPeso molecular:517.71FK-143
CAS:<p>FK-143 is a 5-alpha reductase inhibitor.</p>Fórmula:C40H44N2O3Cor e Forma:SolidPeso molecular:600.79BJ-2302
CAS:<p>BJ-2302 is a potent SRC inhibitor that curbs MDA-MB-231 cell invasion, metastasis, and TNBC proliferation better than Z-FL-COCHO or batimastat.</p>Fórmula:C9H10N2O2Cor e Forma:SolidPeso molecular:178.19JAS239
CAS:<p>JAS239, a carbocyanine dye, blocks ChoK, reducing breast cancer cell viability and tumor growth detectable via optical imaging.</p>Fórmula:C31H37ClN2O2Cor e Forma:SolidPeso molecular:505.09TOP1362
CAS:<p>TOP1362: a kinase inhibitor for dry eye and ocular inflammation; targets p38α, Syk, Src, Lck; reduces cytokines and cell infiltration.</p>Fórmula:C43H51N7O8SCor e Forma:SolidPeso molecular:825.97Ibiglustat hydrochloride
CAS:<p>Ibiglustat hydrochloride is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor.</p>Fórmula:C20H25ClFN3O2SCor e Forma:SolidPeso molecular:425.95BPN-14136
CAS:<p>BPN-14136 is a potent RBP4 antagonist.</p>Fórmula:C20H20F3N3O2Cor e Forma:SolidPeso molecular:391.39DJT06001
CAS:<p>DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.</p>Fórmula:C21H20ClN3O5SCor e Forma:SolidPeso molecular:461.92ANTHRAQUINONE-2-CARBOXYLIC ACID
CAS:<p>Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of</p>Fórmula:C15H8O4Pureza:99.61% - 99.83%Cor e Forma:SolidPeso molecular:252.22Caspofungin
CAS:<p>Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses.</p>Fórmula:C52H88N10O15Cor e Forma:SolidPeso molecular:1093.31VS-II-173
CAS:<p>VS-II-173 is a novel potent Pim1 and Pim3 inhibitor, selectively inducing AML cell death.</p>Fórmula:C14H8N4O2Cor e Forma:SolidPeso molecular:264.24PH11
CAS:<p>PH11, a FAK inhibitor, reactivates TRAIL apoptosis in PANC-1 cells by reducing c-FLIP and inhibiting FAK/PI3K/AKT.</p>Fórmula:C22H22N6O5Cor e Forma:SolidPeso molecular:450.45JG-231
CAS:<p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>Fórmula:C22H18BrCl2N3OS4Pureza:99.79%Cor e Forma:SolidPeso molecular:619.47E 5531
CAS:<p>E 5531 is a novel synthetic lipopolysaccharide antagonist.</p>Fórmula:C73H136N2O22P2Cor e Forma:SolidPeso molecular:1455.81Flutimide
CAS:<p>Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.</p>Fórmula:C12H18N2O3Cor e Forma:SolidPeso molecular:238.28F-1394
CAS:<p>F-1394 is an ACAT inhibitor that reduces atherosclerosis and neointimal thickening without changing serum cholesterol.</p>Fórmula:C33H61N3O6Cor e Forma:SolidPeso molecular:595.85CM-546
CAS:<p>CM-546 is the trans-isomer of CM-414, and a dual inhibitor of PDE5 and HDACs.</p>Fórmula:C23H29N5O4Cor e Forma:SolidPeso molecular:439.51Gepotidacin mesylate dihydrate
CAS:<p>Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.</p>Fórmula:C25H36N6O8SPureza:99.85%Cor e Forma:SolidPeso molecular:580.65GK-128 hydrochloride
CAS:<p>GK-128 hydrochloride is a 5-hydroxytryptamine(3) receptor antagonist and an anti-emetic.</p>Fórmula:C18H15ClN2OSCor e Forma:SolidPeso molecular:342.842,4'-Dihydroxybenzophenone
CAS:<p>2,4'-Dihydroxybenzophenone can effectively protect C57BL/6J mice from APAP-induced hepatotoxicity.</p>Fórmula:C13H10O3Pureza:99.85%Cor e Forma:SolidPeso molecular:214.22STX2845
CAS:<p>STX2845 is a nonsteroidal Sulfamate Derivative that inhibit Carbonic Anhydrase IX (Ki = 2 nM)</p>Fórmula:C19H24N2O6SCor e Forma:SolidPeso molecular:408.47BITMC
CAS:<p>BITMC is a novel potent IDO1 inhibitor.</p>Fórmula:C20H14BrN5OSCor e Forma:SolidPeso molecular:452.33V11294A
CAS:V11294A, a PDE4 inhibitor, maintains anti-inflammatory effects for 24h+ with a 300mg dose in humans, sans side effects.Fórmula:C23H31N5O2Cor e Forma:SolidPeso molecular:409.52PF-06371900
CAS:<p>PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).</p>Fórmula:C17H16N6O2SCor e Forma:SolidPeso molecular:368.41TH251
CAS:<p>TH251 is a highly selective antagonist of LIMK1 and LIMK2 (LIMK1/2).</p>Fórmula:C22H22N2O3SCor e Forma:SolidPeso molecular:394.49JTP-4819
CAS:<p>JTP-4819: potent PEP inhibitor, may treat Alzheimer's, boosts brain peptides and acetylcholine, aiding memory.</p>Fórmula:C19H25N3O4Cor e Forma:SolidPeso molecular:359.42PF-06663195
CAS:<p>PF-06663195 is a potent inhibitor of β-site amyloid precursor protein (APP) Cleaving Enzyme 1 (BACE1, β-Secretase 1).</p>Fórmula:C18H18F3N3O2SCor e Forma:SolidPeso molecular:397.41SNU-BP
CAS:<p>SNU-BP activates PPAR-gamma, blocks LPS-induced NO, reduces inflammation, and promotes M2 microglial anti-inflammatory shift.</p>Fórmula:C31H31N3O7Cor e Forma:SolidPeso molecular:557.59SF0166
CAS:<p>SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.</p>Fórmula:C23H27F2N5O4Cor e Forma:SolidPeso molecular:475.49PF-06672131
CAS:<p>PF-06672131 is a selective EGFR kinase inhibitor.</p>Fórmula:C23H21ClFN5O2Cor e Forma:SolidPeso molecular:453.97-Acetoxy-4-methylcoumarin
CAS:<p>7-Acetoxy-4-methylcoumarin is an inhibitor of GST and can inhibit AFB1-DNA binding in vitro.Cost-effective and quality-assured.</p>Fórmula:C12H10O4Pureza:88.44% - 97.10%Cor e Forma:Beige Crystalline Flakes And NeedlesPeso molecular:218.21PF-06658607
CAS:<p>PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor.</p>Fórmula:C27H24N6O2Cor e Forma:SolidPeso molecular:464.52Xylarianaphthol-1
CAS:<p>Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.</p>Fórmula:C16H20BrFN2O2Cor e Forma:SolidPeso molecular:371.24FTI-249
CAS:<p>FTI-249 is a Farnesyltransferase inhibitor, which potently inhibited FTase (IC50 = 100–200 nM).</p>Fórmula:C15H23N3O3S2Cor e Forma:SolidPeso molecular:357.49AS2575959
CAS:<p>AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.</p>Fórmula:C32H35NaO7Cor e Forma:SolidPeso molecular:554.6148LH-708
CAS:<p>LH-708 is an inhibitor of cystine stone formation for treatment of cystinuria.</p>Fórmula:C16H36Cl4N6O2S2Cor e Forma:SolidPeso molecular:550.42ZEN-2759
CAS:<p>ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).</p>Fórmula:C17H16N2O2Pureza:99.36%Cor e Forma:SolidPeso molecular:280.32CHF-6366
CAS:<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Fórmula:C42H48N6O8Cor e Forma:SolidPeso molecular:764.87BAY 61-3606 HCl
CAS:<p>BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.</p>Fórmula:C20H19ClN6O3Cor e Forma:SolidPeso molecular:426.86EXP-561 monohydrate
CAS:<p>EXP-561 monohydrate is an investigational drug that acts as an inhibitor of the reuptake of serotonin, dopamine, and norepinephrine.</p>Fórmula:C14H22ClNOCor e Forma:SolidPeso molecular:255.79PF-04479745 tartrate
CAS:<p>PF-04479745 (PF-4479745) is a selective 5-HT2C agonist with EC50 10 nM, effective in canine SUI models, not targeting 5-HT2A/B.</p>Fórmula:C21H28N4O6Cor e Forma:SolidPeso molecular:432.477
