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Termina em 31 de dez.( faltam 7 dias )
Berotralstat HCl
CAS:Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.Fórmula:C30H28Cl2F4N6OCor e Forma:SolidPeso molecular:635.4886GPA512
CAS:<p>GPA512 is a prodrug of aliellalactone, inhibiting STAT3 and preventing the transcription of STAT3 regulated genes.</p>Fórmula:C17H25NO6SCor e Forma:SolidPeso molecular:371.45Bizine dihydrochloride
CAS:Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.Fórmula:C18H25Cl2N3OCor e Forma:SolidPeso molecular:370.32LASSBio-1829 HCl
CAS:LASSBio-1829 HCl is an orally active IKK2 inhibitor.Fórmula:C25H19ClN4OCor e Forma:SolidPeso molecular:426.9V-125
CAS:V-125 is an agonist of retinoid X receptors.Fórmula:C23H30N2O2Cor e Forma:SolidPeso molecular:366.5Indinavir monohydrate
CAS:Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.Fórmula:C36H49N5O5Cor e Forma:SolidPeso molecular:631.82BP-5-087
CAS:BP-5-087 is a STAT3 inhibitor, combining with BCR-ABL1 inhibition to overcome kinase-independent resistance in chronic myeloid leukemia.Fórmula:C36H30F8N2O6SCor e Forma:SolidPeso molecular:770.69Tofacitinib HCl
CAS:Tofacitinib (tasocitinib, CP-690550) is a JAK inhibitor impacting phosphorylation/activation of STATs with varied IC50 values.Fórmula:C16H21ClN6OCor e Forma:SolidPeso molecular:348.835UAWJ-247
CAS:UAWJ-247 is a SARS-CoV-2 Main Protease inhibitor (IC50 = 45 nM).Fórmula:C24H28N3NaO8SCor e Forma:SolidPeso molecular:541.55WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Fórmula:C21H24F3N7O2Pureza:>99.99% - ≥95%Cor e Forma:SolidPeso molecular:463.46Milvexian TFA
CAS:Milvexian (BMS-986177/JNJ-70033093) is a factor XIa inhibitor with Ki=44 nM for kallikrein, Ki=35 nM for chymotrypsin, 32% bioavailability.Fórmula:C30H26Cl2F5N9O4Cor e Forma:SolidPeso molecular:742.49GSK1379767A
CAS:GSK1379767A is a dual inhibitor of BPTF and Brd4.Fórmula:C26H30N6O6Cor e Forma:SolidPeso molecular:522.55NY0173
CAS:<p>NY0173 is a potent exchange protein activated by cAMP antagonists.</p>Fórmula:C18H15Cl3N4O2Cor e Forma:SolidPeso molecular:425.7NY0123
CAS:NY0123 is an active EPAC antagonist with low micromolar inhibitory activity.Fórmula:C16H13Cl3N4O2Cor e Forma:SolidPeso molecular:399.66Fadaltran
CAS:Fadaltran is an α2-adrenoreceptor antagonist.Fórmula:C24H29N5O2Cor e Forma:SolidPeso molecular:419.52P7170
CAS:<p>P7170 is an anti-cancer agent active as an mTORC1/C2 and activin receptor-like kinase 1 (ALK1) inhibitor.</p>Fórmula:C21H16F3N9Cor e Forma:SolidPeso molecular:451.42OAT-177
CAS:OAT-177 is a potent, selective, orally active acidic mammalian chitinase (AMCase) inhibitor.Fórmula:C19H29ClN6Cor e Forma:SolidPeso molecular:376.93Sonidegib metabolite M25
CAS:Sonidegib metabolite M25 is a smoothened (SMO) antagonist.Fórmula:C26H26F3N3O4Cor e Forma:SolidPeso molecular:501.5THIQ-40
CAS:THIQ-40: potent ERα antagonist, oral SERD with antitumor effects.Fórmula:C28H29NO3Cor e Forma:SolidPeso molecular:427.53WZB117
CAS:WZB117 inhibits GLUT1; IC50 ~10μM slows A549 lung & MCF7 breast cancer cell growth.Fórmula:C20H13FO6Pureza:99.03% - 99.18%Cor e Forma:SolidPeso molecular:368.31LFS-829
CAS:LFS-829: small molecule, inhibits exportin-1, low nanomolar activity, orally reverses colitis in mice, low toxicity, promising for clinical trials.Fórmula:C13H9F6NOS2Cor e Forma:SolidPeso molecular:373.34FFA3-Antagonist-6
CAS:FFA3-Antagonist-6 is a PAM-antagonist of the function of C3 at FFA3.Fórmula:C30H28N2O3Cor e Forma:SolidPeso molecular:464.55NVP-BHS345
CAS:<p>NVP-BHS345 is a dual inhibitor of TORC1 and TORC2.</p>Fórmula:C25H20N6OCor e Forma:SolidPeso molecular:420.47Eptapirone fumarate
CAS:Eptapirone (F11440) is a strong 5HT1A agonist with high anxiolytic and antidepressant effects, more potent than buspirone and flesinoxan.Fórmula:C20H27N7O6Cor e Forma:SolidPeso molecular:461.479YM-60828 dihydrochloride
CAS:YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease.Fórmula:C27H33Cl2N5O5SCor e Forma:SolidPeso molecular:610.55Desmethyl atenolol
CAS:Desmethyl atenolol is an impurity of Atenolol -- a selective β1 receptor antagonist.Fórmula:C13H20N2O3Cor e Forma:SolidPeso molecular:252.31Methazolamide-d6
CAS:<p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>Fórmula:C5H2D6N4O3S2Cor e Forma:SolidPeso molecular:242.31NPC-18915
CAS:NPC-18915 is a benzofuran compound, inhibitor of neutophil activation.Fórmula:C23H16O3Cor e Forma:SolidPeso molecular:340.37ER-34122
CAS:<p>ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity.</p>Fórmula:C27H26ClN3O5Pureza:>99.99%Cor e Forma:SolidPeso molecular:507.96Navoximod phosphate
CAS:<p>Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic.</p>Fórmula:C18H24FN2O6PCor e Forma:SolidPeso molecular:414.37Z-IETD-FMK
CAS:<p>Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.</p>Fórmula:C30H43FN4O11Pureza:95% - 99.81%Cor e Forma:SolidPeso molecular:654.68Tinostamustine HCl
CAS:Tinostamustine (EDO-S101) is an alkylating HDACi fusion molecule, enhancing potency and overcoming drug resistance.Fórmula:C19H29Cl3N4O2Cor e Forma:SolidPeso molecular:451.82GI261520A
CAS:GI261520A is a potent egfr/erbb2 dual inhibitorFórmula:C22H19N3O2Cor e Forma:SolidPeso molecular:357.41NC-2100
CAS:<p>NC-2100 is an aperoxisome proliferator-activated receptor-gamma (PPARgamma) activator.</p>Fórmula:C20H16N2O3SCor e Forma:SolidPeso molecular:364.42APC-366 HCl
CAS:APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.Fórmula:C22H29ClN6O4Cor e Forma:SolidPeso molecular:476.96AM92016
CAS:AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity.Fórmula:C26H30Cl2N2O6SCor e Forma:SolidPeso molecular:569.49NL-103
CAS:NL-103, a dual-targeting compound, inhibits HDACs & Hh pathway, countering vismodegib-resistant Smo mutations.Fórmula:C26H27Cl2N5O4Cor e Forma:SolidPeso molecular:544.43AZD1446 HCl
CAS:AZD1446 (TC-6683) is a selective α4β2 receptor agonist, showing promise in treating cognitive deficits and Alzheimer's.Fórmula:C11H14Cl2N2O2Cor e Forma:SolidPeso molecular:277.15AQ 148
CAS:<p>AQ 148 is a potent competitive inhibitor of HIV-1 PR.</p>Fórmula:C30H37N3O4Cor e Forma:SolidPeso molecular:503.63Atrasentan sodium
CAS:Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.Fórmula:C29H37N2NaO6Cor e Forma:SolidPeso molecular:532.61Enecadin HCl
CAS:<p>Enecadin HCl is a voltage-dependent sodium and calcium channel blocker.</p>Fórmula:C21H29ClFN3OCor e Forma:SolidPeso molecular:393.93Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Fórmula:C21H28FN3O7Pureza:98.24% - 99.79%Cor e Forma:SolidPeso molecular:453.46VU590 HCl
CAS:VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM).Fórmula:C24H34Cl2N4O7Cor e Forma:SolidPeso molecular:561.457S 16020-2
CAS:<p>S 16020-2 is an olivacine derivative, and DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors.</p>Fórmula:C22H26Cl2N4O2Cor e Forma:SolidPeso molecular:449.376DDR1-IN-1 dihydrochloride
CAS:DDR1-IN-1 dihydrochloride: potent DDR1 kinase inhibitor; IC50=105 nM; 4x less effective on DDR2 (IC50=413 nM).Fórmula:C30H33Cl2F3N4O3Cor e Forma:SolidPeso molecular:625.51Galloflavin Potassium
CAS:<p>Galloflavin Potassium is an inhibitor of lactate dehydrogenase.</p>Fórmula:C12H5KO8Cor e Forma:SolidPeso molecular:316.26XM 412
CAS:XM 412, also known as DMP 450, is an HIV protease inhibitor.Fórmula:C35H44N4O9S2Cor e Forma:SolidPeso molecular:728.876IND8
CAS:IND8 is a selective and potent α7-nAChR agonist.Fórmula:C17H19N5Cor e Forma:SolidPeso molecular:293.37Clorgyline
CAS:Clorgyline,M&B 9302, an irreversible and selective MAO-A inhibitor with the advantages of oral activity and blood-brain barrier permeability, antidepressant.Fórmula:C13H15Cl2NOPureza:98.39%Cor e Forma:SolidPeso molecular:272.17Pimodivir tosylate
CAS:Pimodivir (VX-787/JNJ-872) inhibits influenza by targeting PB2, with KD 24 nM and EC50 1.6 nM, effective against various strains, including NAI-resistant ones.Fórmula:C27H27F2N5O5SCor e Forma:SolidPeso molecular:571.6
