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Termina em 31 de dez.( faltam 8 dias )
MNF
CAS:<p>MNF, or 3,4-MNF, blocks AhR, limits UVR immune impact, and boosts Tregs in mouse CHS.</p>Fórmula:C16H11NO5Cor e Forma:SolidPeso molecular:297.26PS77
CAS:<p>PS77 is a Pkh inhibitor directed to the PIF-pocket with increased selectivity for C. albicans Pkh2.</p>Fórmula:C23H18Cl2O3S2Cor e Forma:SolidPeso molecular:477.42CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63QS inhibitor 2
CAS:QS inhibitor 2 is a novel potent inhibitor of quorum sensing (QS) pathways.Fórmula:C18H15ClN4O2S2Cor e Forma:SolidPeso molecular:418.92Lig3
CAS:Lig3 is an inhibitor against high-risk strains of human papillomavirus (HPV) E6 oncoprotein.Fórmula:C20H17ClN4O3Cor e Forma:SolidPeso molecular:396.833-Allylphenol
CAS:3-Allylphenol is an inhibitor of dopamine β-hydroxylase (DBH; Ki = 12 mM).Fórmula:C9H10OCor e Forma:SolidPeso molecular:134.18JFN05510
CAS:Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Fórmula:C50H68N7O9PSiCor e Forma:SolidPeso molecular:970.18FGF/PDGF/VEGF RTK Inhibitor
CAS:<p>Potent, reversible ATP-competitive inhibitor for PDGFRβ, FGFR-1, VEGFR-2 (IC50: 20, 90, 240 nm); hinders VEGF-driven HMVEC growth (EC50: 420 nm).</p>Fórmula:C16H11N3O2Cor e Forma:SolidPeso molecular:277.28Eleclazine
CAS:Eleclazine (GS-6615) is a novel and selective voltage-gated sodium channel inhibitor with antiarrhythmic properties that reduces peak sodium current (INaP).Fórmula:C21H16F3N3O3Pureza:98.67%Cor e Forma:SolidPeso molecular:415.37ID110460003
CAS:ID110460003 is a novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist.Fórmula:C20H25N3O2Cor e Forma:SolidPeso molecular:339.43SGK1 inhibitor
CAS:SGK1 inhibitor targets SGK1/2 over SGK3, blocks GSK3β phosphorylation, lowers HCC1954 cell viability with BYL719, and reduces tumor growth in mice.Fórmula:C17H12Cl2N6O2SCor e Forma:SolidPeso molecular:435.29Flufenacet
CAS:Flufenacet is a herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis.Fórmula:C14H13F4N3O2SCor e Forma:SolidPeso molecular:363.33CM304
CAS:CM304 is a highly selective sigma-1 receptor antagonist.Fórmula:C18H26ClFN2OSCor e Forma:SolidPeso molecular:372.93GSK369796 Dihydrochloride
CAS:GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Fórmula:C20H24Cl3N3OPureza:>99.99%Cor e Forma:SolidPeso molecular:428.78PSB-12054
CAS:PSB-12054 is a potent P2X4 receptor inhibitor. PSB-12054 has IC(50) of 0.189 μM and good selectivity versus the other human P2X receptor subtypes.Fórmula:C20H15NO3Cor e Forma:SolidPeso molecular:317.34AS-1940477 hydrobromide
CAS:AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.Fórmula:C24H23BrFN5O2Cor e Forma:SolidPeso molecular:512.38DDD01035881
CAS:DDD01035881 is a anti-malarial drug that blocks parasite-to-mosquito transmission by targeting the Plasmodium vesicle membrane protein Pfs16.Fórmula:C14H14BrNO4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:404.3MMG-0358
CAS:MMG-0358 is a novel potent IDO1 inhibitor, showing low cytotoxicity and higher selectivity for IDO1 over TDO enzyme.Fórmula:C8H6ClN3OCor e Forma:SolidPeso molecular:195.61(±)-C3001a
CAS:(RS)-C3001a is the racemic mixture of C3001a (CAS: 2415154-29-7). C3001a is a selective activator of the TREK channel.Fórmula:C21H20N2O3SPureza:99.13%Cor e Forma:SolidPeso molecular:380.46Pimprinine
CAS:Pimprinine: an alkaloid, inhibits MAO, and has anticonvulsant properties.Fórmula:C12H10N2OCor e Forma:SolidPeso molecular:198.22Cupferron
CAS:<p>Cupferron is a superoxide dismutase inhibitor.</p>Fórmula:C6H9N3O2Cor e Forma:SolidPeso molecular:155.16BZX2
CAS:BZX2 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.Fórmula:C17H13NO6Cor e Forma:SolidPeso molecular:327.29HG-10-102-01
CAS:HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Fórmula:C17H20ClN5O3Pureza:99.59%Cor e Forma:SolidPeso molecular:377.83Aminogenistein
CAS:Aminogenistein inhibits protein-tyrosine kinase activity of p56lck.Fórmula:C15H11NO3Cor e Forma:SolidPeso molecular:253.25TUN-92046
CAS:<p>TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.</p>Fórmula:C7H10O5Pureza:95.48% - 98.58%Cor e Forma:SolidPeso molecular:174.15DAU 5884 HCl
CAS:DAU 5884 HCl is an M3 receptor antagonistFórmula:C17H21N3O3Cor e Forma:SolidPeso molecular:315.37Ravidasvir HCl
CAS:Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.Fórmula:C42H52Cl2N8O6Cor e Forma:SolidPeso molecular:835.828KRIBB3
CAS:KRIBB3: novel anticancer microtubule inhibitor; halts MDA-MB-231 cell migration/invasion by targeting Hsp27 phosphorylation.Fórmula:C19H19NO4Cor e Forma:SolidPeso molecular:325.36PD-128763
CAS:PD-128763 is a poly(ADP-ribose) polymerase inhibitor exhibiting radiosensitising effects, enhancing radiation-induced cell killing in X-ray-irradiated cells.Fórmula:C10H11NOCor e Forma:SolidPeso molecular:161.20Fmoc-12-aminododecanoic acid
CAS:Fmoc-12-aminododecanoic acid has Fmoc-protected amine, carboxylic ends, used as PROTAC linker, deprotects to free amine for conjugation.Fórmula:C27H35NO4Cor e Forma:SolidPeso molecular:437.57R995045
CAS:<p>R995045 is a novel delta opioid receptor agonist chemotype.</p>Fórmula:C16H14N4O3SCor e Forma:SolidPeso molecular:342.37Remacemide
CAS:<p>Remacemide is a low-affinity NMDA antagonist with sodium channel blocking properties.</p>Fórmula:C17H20N2OCor e Forma:SolidPeso molecular:268.35Fadrozole
CAS:Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)Fórmula:C14H13N3Pureza:99.47%Cor e Forma:SolidPeso molecular:223.27Fmoc-7-amino-heptanoic acid
CAS:Fmoc-7-amino-heptanoic acid: used for PROTAC linker synthesis, has Fmoc-protected amine and carboxylic ends for conjugation reactions.Fórmula:C22H25NO4Cor e Forma:SolidPeso molecular:367.44CS-0045569
CAS:CS-0045569 (ZUN24972) is a drug synthesis intermediate reported in WO 2020086857 as WDR5 inhibitor component.Fórmula:C12H12O6Cor e Forma:SolidPeso molecular:252.22N-Fmoc-8-aminooctanoic acid
CAS:N-Fmoc-8-aminooctanoic acid: a PROTAC linker with deprotectable Fmoc-amine and reactive carboxylic end for stable amide bonds.Fórmula:C23H27NO4Cor e Forma:SolidPeso molecular:381.46Gilteritinib hemifumarate
CAS:<p>Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of</p>Fórmula:C29H44N8O3C4H4O4Pureza:99.78%Cor e Forma:SolidPeso molecular:610.75ABI-274
CAS:<p>ABI-274 is a novel potent colchicine binding site inhibitor (CBSI) and tubulin inhibitor.</p>Fórmula:C20H20N2O4Cor e Forma:SolidPeso molecular:352.385-MPEP
CAS:5-MPEP blocks mGlu5, countering MPEP and CDPPB effects at its allosteric site.Fórmula:C14H11NCor e Forma:SolidPeso molecular:193.24Fmoc-5-aminopentanoic acid
CAS:Fmoc-5-aminopentanoic acid: alkane, Fmoc-protected amine, carboxyl group, PROTAC linker, deprotects to free amine, forms amides with activators.Fórmula:C20H21NO4Cor e Forma:SolidPeso molecular:339.39TP-S1-68
CAS:TP-S1-68 is a Type-I inhibitor of TIE-2.Fórmula:C15H9ClN4SCor e Forma:SolidPeso molecular:312.78Fadrozole HCl hydrate
CAS:Fadrozole is a selective inhibitor of aromatase. It also effective in the treatment of estrogen-dependent diseases including breast cancer.Fórmula:C14H13N3ClHH2OPureza:98%Cor e Forma:SolidPeso molecular:268.74E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Fórmula:C21H29Cl2N3O3SPureza:99.31% - 99.87%Cor e Forma:SolidPeso molecular:474.44Ofloxacin HCl
CAS:Ofloxacin HCl, a synthetic antibacterial fluoroquinolone, blocks bacterial DNA gyrase to stop DNA replication.Fórmula:C18H21ClFN3O4Cor e Forma:SolidPeso molecular:397.83Zidovudine glucuronide
CAS:Zidovudine glucuronide: an NRTI antiretroviral for HIV/AIDS treatment; blocks HIV reverse transcriptase, stops viral DNA formation.Fórmula:C16H21N5O10Cor e Forma:SolidPeso molecular:443.37Enrofloxacin-d5
CAS:<p>Enrofloxacin-d5 is a deuterium marker for Enrofloxacins.(BAY-Vp2674) is an antibiotic that acts against Mycoplasma bovis and has a MIC90 of 0.312 μg/mL.</p>Fórmula:C19H22FN3O3Cor e Forma:SolidPeso molecular:364.43ID110460002
CAS:ID110460002 is a novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist.Fórmula:C20H25FN4OCor e Forma:SolidPeso molecular:356.44Fmoc-4-aminobutanoic acid
CAS:Fmoc-4-aminobutanoic acid, a PROTAC linker, has Fmoc-protected amine and carboxyl groups, used in conjugations.Fórmula:C19H19NO4Cor e Forma:SolidPeso molecular:325.365-hydroxy Isatin
CAS:5-hydroxy Isatin inhibits MAO-A and ANP-induced particulate guanylyl cyclase in rat brain/heart.Fórmula:C8H5NO3Cor e Forma:SolidPeso molecular:163.13
