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Termina em 31 de dez.( faltam 8 dias )
CK2α-IN-1
CAS:<p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>Fórmula:C16H11N3O4SPureza:98%Cor e Forma:SolidPeso molecular:341.347-Methoxyisoflavone
CAS:7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).Fórmula:C16H12O3Pureza:99.93% - 99.94%Cor e Forma:SolidPeso molecular:252.26GSK3-IN-2
CAS:<p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>Fórmula:C17H19N3OSPureza:98.8%Cor e Forma:SolidPeso molecular:313.42MMV688845
CAS:MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.Fórmula:C24H25N3O3SCor e Forma:SolidPeso molecular:435.54VU6019650
VU6019650: potent M5 mAChR antagonist, IC50=36nM. May help with OUD, crosses blood-brain barrier, affects VTA dopamine neurons.Fórmula:C18H22FN3O3S2Cor e Forma:SolidPeso molecular:411.51SERT-IN-2
SERT-IN-2, a potent SERT inhibitor (IC 50 = 0.58 nM), exhibits promising efficacy as an anti-depressant.Cor e Forma:SolidCamA-IN-1
CamA-IN-1, specific Clostridioides difficile methyltransferase inhibitor, IC50 = 0.4μM, Kd = 0.2μM, targets CDI research.Fórmula:C23H36N6O6Cor e Forma:SolidPeso molecular:492.57BTK-IN-22
CAS:BTK-IN-22 is a selective BTK inhibitor with IC50 of 0.9 nM; also targets BLX, BMX (IC50s: 1.4, 1.2 nM); better selectivity than Ibrutinib.Fórmula:C26H26N6O2Cor e Forma:SolidPeso molecular:454.52BTK-IN-23
CAS:BTK-IN-23: BTK inhibitor, IC50=12.8 nM; also blocks BLX (35.6 nM), BMX (5.7 nM); better selectivity than Ibrutinib.Fórmula:C27H28N6O2Cor e Forma:SolidPeso molecular:468.55FABP-IN-2
CAS:FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.Fórmula:C25H21ClN2O3Cor e Forma:SolidPeso molecular:432.9MLKL-IN-5
CAS:MLKL-IN-5 is a potent MLKL inhibitor that mediates necroptosis .Fórmula:C18H20N6O4SCor e Forma:SolidPeso molecular:416.45HBV-IN-29
CAS:HBV-IN-29 (ex8), a flavone derivative, inhibits cccDNA in HBV research.Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84HBV-IN-30
CAS:<p>HBV-IN-30, a flavone derivative, inhibits cccDNA in HBV research.</p>Fórmula:C22H18BrClO6Cor e Forma:SolidPeso molecular:493.73HBV-IN-31
CAS:HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.Fórmula:C23H18ClNO6Cor e Forma:SolidPeso molecular:439.85HBV-IN-32
CAS:HBV-IN-32 is a strong cccDNA inhibitor with an IC50 of 0.14 µM against HBsAg, also halting cell growth.Fórmula:C22H19ClO5SCor e Forma:SolidPeso molecular:430.9Vonifimod
CAS:Vonifimod is an immunomodulator .Fórmula:C17H34N4O2Cor e Forma:SolidPeso molecular:326.48SRI-42127
CAS:SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.Fórmula:C19H20N6OPureza:99.66%Cor e Forma:SolidPeso molecular:348.4DC-BPi-03
CAS:DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC 50 of 698.3 nM and a K d of 2.81 μM .Fórmula:C14H14N4O2SPureza:98.96%Cor e Forma:SolidPeso molecular:302.35mHTT-IN-1
CAS:mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.Fórmula:C18H19N7OSCor e Forma:SolidPeso molecular:381.45C-178
CAS:<p>C-178 inhibits STING by binding Cys91, blocking palmitoylation and TBK1 activation in HEK293T cells.</p>Fórmula:C17H10N2O5Pureza:97.69%Cor e Forma:SolidPeso molecular:322.27Fabimycin
CAS:Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Fórmula:C23H25ClN4O3Cor e Forma:SolidPeso molecular:440.92ZIKV-IN-3
CAS:ZIKV-IN-3, an andrographolide derivative, inhibits ZIKV NS5 MTase (IC50: 18.34 μM) and replication. Used for Zika virus research.Fórmula:C39H41NO4Cor e Forma:SolidPeso molecular:587.75WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Fórmula:C13H15BrCl2N2O4SPureza:98.09%Cor e Forma:SolidPeso molecular:446.14iBRD4-BD1
CAS:iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Fórmula:C29H30F3N5OCor e Forma:SolidPeso molecular:521.58TDI-11861
CAS:TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.Fórmula:C22H25ClF2N6O3Cor e Forma:SolidPeso molecular:494.92MurA-IN-3
CAS:MurA-IN-3, a reversible pyrrolidinedione-based MurA inhibitor, exhibits an IC50 of 4.5 μM against MurA and demonstrates antibacterial activity [1].Fórmula:C27H23ClN2O5SCor e Forma:SolidPeso molecular:523APE1-IN-2
CAS:<p>APE1-IN-2 (AP1), a Pt(IV) proagent, targets APE1 protein, induces DNA damage, and triggers apoptosis with anticancer effects.</p>Fórmula:C9H12Cl2N4O5PtPureza:98%Cor e Forma:SolidPeso molecular:522.21Nucleozin
CAS:Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.Fórmula:C21H19ClN4O4Pureza:97.72%Cor e Forma:SolidPeso molecular:426.85AXL-IN-13
CAS:AXL-IN-13: potent, oral AXL inhibitor, IC50=1.6nM, Kd=0.26nM, anti-cancer, inhibits EMT, cell migration & invasion.Fórmula:C34H41FN6O5Pureza:99.95%Cor e Forma:SolidPeso molecular:632.72ATR-IN-20
ATR-IN-20: potent ATR inhibitor, IC50=3nM; inhibits mTOR, IC50=18nM; selective vs PI3Kα, ATM, DNA-PK; good pharmacokinetics; anticancer.Fórmula:C29H31N5O4SCor e Forma:SolidPeso molecular:545.65FAAH-IN-7
<p>FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.</p>Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53BTK-IN-17
BTK-IN-17: selective, oral BTK inhibitor, IC50=13.7 nM, reduces p-BTK Y223/p-PLCγ2 Y1217, anti-inflammatory.Fórmula:C26H23N7O2Cor e Forma:SolidPeso molecular:465.51ALR2-IN-2
ALR2-IN-2 inhibits ALR2 (27 nM IC50) & ALR1 (228 nM IC50), used in diabetes complication research.Fórmula:C17H11FN2O2S2Cor e Forma:SolidPeso molecular:358.41ALR2-IN-3
ALR2-IN-2 inhibits ALR2 strongly (IC50: 22 nM) and ALR1 less (IC50: 116 nM), used in diabetes complication studies.Fórmula:C17H12N2O3S2Cor e Forma:SolidPeso molecular:356.42TrkA-IN-3
TrkA-IN-3: potent allosteric TrkA inhibitor, IC50=22.4 nM, >8000x selective over TrkB/C, for pain research.Fórmula:C24H17F3N4O3Cor e Forma:SolidPeso molecular:466.41TrkA-IN-4
TrkA-IN-4, a potent, orally active and allosteric TrkA inhibitor, is a prodrug of TrkA-IN-3 . TrkA-IN-4 exhibits potent antinociceptive effects [1] .Fórmula:C27H21F3N4O5Cor e Forma:SolidPeso molecular:538.47Mps1-IN-5
CAS:Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.Fórmula:C24H25N9Cor e Forma:SolidPeso molecular:439.52RET-IN-20
RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.Fórmula:C32H33FN6O4Cor e Forma:SolidPeso molecular:584.64Ursocholic acid
CAS:Ursocholic acid, a bile acid found predominantly in bile of mammals.Fórmula:C24H40O5Pureza:98.89% - 99.62%Cor e Forma:SolidPeso molecular:408.57AXL-IN-14
CAS:AXL-IN-14: orally active, potent AXL inhibitor (IC50=0.8 nM); hinders Gas6/AXL migration, invasion; lowers p-AXL, p-AKT; anti-tumor.Fórmula:C32H24F2N4O4Pureza:98%Cor e Forma:SolidPeso molecular:566.55DENV-IN-7
CAS:DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.Fórmula:C24H22O8Cor e Forma:SolidPeso molecular:438.43DENV-IN-9
CAS:DENV-IN-9 is a DENV2 inhibitor with an EC 50 of 0.88 μM .Fórmula:C15H9BrO5Cor e Forma:SolidPeso molecular:349.13(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Fórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6(S)-ZG197
(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at aFórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6FGFR-IN-9
FGFR-IN-9: oral FGFR inhibitor, IC50: 17.1 nM (FGFR4 WT), 29.6 (FGFR3), 30.7 (V550L), 46.7 (FGFR2), 64.3 nM (FGFR1).Fórmula:C25H28N6O3SCor e Forma:SolidPeso molecular:492.59JZP-MA-13
JZP-MA-13: selective α/β-hydrolase domain 6 inhibitor, IC 50 392 nM, doesn't inhibit MAGL/ABHD12/FAAH, used in PET imaging.Fórmula:C14H15FN4O3SCor e Forma:SolidPeso molecular:338.36BTK-IN-18
CAS:<p>BTK-IN-18 is a potent, reversible inhibitor of Bruton's tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 µM.</p>Fórmula:C20H22Cl2N6OCor e Forma:SolidPeso molecular:433.33BTK-IN-19
CAS:BTK-IN-19 is a reversible BTK inhibitor with an IC 50 of <0.001 μM .Fórmula:C21H22Cl2N6OCor e Forma:SolidPeso molecular:445.35(E)-2-Decenoic acid
CAS:(E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the mandibular gland secretions of honeybees.Fórmula:C10H18O2Pureza:98%Cor e Forma:SolidPeso molecular:170.25
