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Termina em 31 de dez.( faltam 7 dias )
BTK-IN-19
CAS:BTK-IN-19 is a reversible BTK inhibitor with an IC 50 of <0.001 μM .Fórmula:C21H22Cl2N6OCor e Forma:SolidPeso molecular:445.35(E)-2-Decenoic acid
CAS:(E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the mandibular gland secretions of honeybees.Fórmula:C10H18O2Pureza:98%Cor e Forma:SolidPeso molecular:170.25CLK1-IN-2
<p>CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.</p>Fórmula:C16H12Cl2N2O2SCor e Forma:SolidPeso molecular:367.25TBK1-IN-1
CAS:TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.Fórmula:C27H37N7O2Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:491.63RdRP-IN-5
CAS:RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].Fórmula:C23H21N3O5Pureza:98%Cor e Forma:SolidPeso molecular:419.43PARL-IN-1
PARL-IN-1: Strong PARL blocker, IC50 28 nM, boosts PINK1/Parkin mitophagy.Fórmula:C40H58N6O7Cor e Forma:SolidPeso molecular:734.92MenA-IN-1
MenA IN-1 inhibits MTB's MenA enzyme; IC50=13µM, GIC50=8µM, helps fight tuberculosis spread.Fórmula:C29H36N2O2Cor e Forma:SolidPeso molecular:444.61CB2R-IN-3
CB2R-IN-3 selectively blocks CB2R with high affinity, enhances anti-inflammatory cytokines, and can be used with CB65.Fórmula:C27H42N2OCor e Forma:SolidPeso molecular:410.64Merigolix
CAS:Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist .Fórmula:C36H35F7N4O6Cor e Forma:SolidPeso molecular:752.68DHFR-IN-5
CAS:<p>DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.</p>Fórmula:C18H24N4O4Cor e Forma:SolidPeso molecular:360.41P 218
CAS:P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.Fórmula:C18H25ClN4O4Pureza:98.83%Cor e Forma:SoildPeso molecular:396.87MMV676584
CAS:MMV676584 has anti-tuberculosis avtivity. MMV676584 is a novel drug candidate for eumycetoma .Fórmula:C12H8ClFN2OS2Cor e Forma:SolidPeso molecular:314.79Pyrvinium pamoate
CAS:Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drugFórmula:C26H28N3C23H14O6Pureza:99.76% - >99.99%Cor e Forma:SolidPeso molecular:575.71JAK-IN-24
CAS:JAK-IN-24: JAK inhibitor, IC50: 0.534 nM (4 μM ATP), 24 nM (1mM ATP), STAT5 phosphorylation IC50: 86.171 nM.Fórmula:C20H25N5O2Cor e Forma:SolidPeso molecular:367.44GSK3-IN-3
CAS:<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Fórmula:C24H35N3O4Pureza:99.37%Cor e Forma:SolidPeso molecular:429.55BI-685509
CAS:BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.Fórmula:C34H38N4O5Cor e Forma:SolidPeso molecular:582.69OICR12694
CAS:OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) .Fórmula:C29H28ClF3N8O4Cor e Forma:SolidPeso molecular:645.03Larotinib
CAS:Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.Fórmula:C24H26ClFN4O4Pureza:99.73%Cor e Forma:SolidPeso molecular:488.94P2X7-IN-2
CAS:P2X7-IN-2 is a P2X7 receptor blocker, halts IL-Iβ release (IC50: 0.01 nM), researched for autoimmunity and heart issues.Fórmula:C22H21F4N3O2Cor e Forma:SolidPeso molecular:435.41Ketotifen
CAS:Ketotifen: Oral H1 blocker & mast cell stabilizer, inhibits 6-phosphogluconate dehydrogenase, antiviral, for EAE & asthma prevention research.Fórmula:C19H19NOSCor e Forma:SolidPeso molecular:309.43Articaine
CAS:Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-Fórmula:C13H20N2O3SCor e Forma:SolidPeso molecular:284.37Obtusalin
CAS:<p>Obtusalin, a triterpenoid initially identified in R. dauricum, exhibits UV absorption at 210 nm and possesses antibacterial properties.</p>Fórmula:C30H50O2Cor e Forma:SolidPeso molecular:442.72NP118809
CAS:<p>NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).</p>Fórmula:C32H32N2OPureza:97.74% - 98.68%Cor e Forma:SolidPeso molecular:460.61Quipazine
CAS:<p>Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.</p>Fórmula:C13H15N3Cor e Forma:SolidPeso molecular:213.28Prenderol
CAS:<p>Prenderol, a potent central-nervous-system (CNS) depressant, exhibits anticonvulsant activity.</p>Fórmula:C7H16O2Cor e Forma:SolidPeso molecular:132.2BAP1-IN-1
CAS:BAP1-IN-1 is an inhibitor of the catalytic activity of BRCA1-associated protein 1 (BAP1), which is related to cancer and can be used to study cancer.Fórmula:C18H16N2O2Pureza:98.11%Cor e Forma:SolidPeso molecular:292.33AP 24149
CAS:AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.Fórmula:C23H24N5OPCor e Forma:SolidPeso molecular:417.44SC 34301
CAS:SC 34301 (Enisoprost), a strong oral PGE1 analog, decreases bacterial translocation and increases burned mice survival.Fórmula:C22H36O5Cor e Forma:SolidPeso molecular:380.52BCX-1898
CAS:BCX-1898: Oral cyclopentane-based neuraminidase inhibitor for flu A/B; EC50 <0.01-21µM; effective in mouse models.Fórmula:C17H32N4O3Cor e Forma:SolidPeso molecular:340.46CCG-2046
CAS:CCG-2046 is a chemical inhibitor targeting RGS4, demonstrating an inhibition concentration (IC50) of 4.3 μM for the interaction between RGS4 and Gαo signal.Fórmula:C11H10N4Cor e Forma:SolidPeso molecular:198.22TTT 3002
CAS:TTT 3002: oral FLT3 inhibitor for AML research, blocks D835 mutations, potent at 0.2 nM IC50.Fórmula:C27H23N5O3Cor e Forma:SolidPeso molecular:465.502,3-Diaminopropionic acid
CAS:2,3-Diaminopropionic acid (L-2,3-Diaminopropionic acid) is an amino acid that is a precursor of antibiotics and staphyloferrin B a siderophore produced byFórmula:C3H8N2O2Pureza:99.61% - 99.90%Cor e Forma:SolidPeso molecular:104.11BAY-3827
CAS:BAY-3827 is an AMPK inhibitor with antiproliferative activity and antitumor activity. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.Fórmula:C27H25FN6OPureza:99.90%Cor e Forma:SolidPeso molecular:468.53CAY10581
CAS:CAY10581, a derivative of pyranonaphthoquinone, serves as a highly specific and reversible uncompetitive inhibitor of IDO, demonstrating potency with an IC50Fórmula:C22H21NO4Cor e Forma:SolidPeso molecular:363.41A-943931
CAS:A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.Fórmula:C17H21N5Pureza:99.79%Cor e Forma:SolidPeso molecular:295.38NOS-IN-3
CAS:NOS-IN-3: potent, selective iNOS inhibitor; IC50 of 4.6 µM; spares eNOS; low toxicity; potential for septic shock treatment.Fórmula:C10H15N3OCor e Forma:SolidPeso molecular:193.25TPN729MA
CAS:<p>TPN729MA, a potent PDE5 inhibitor, IC50: 2.28 nM, targets erectile dysfunction research.</p>Fórmula:C29H40N6O8SCor e Forma:SolidPeso molecular:632.73Ac32Az19
CAS:Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressedFórmula:C37H33N3O6Cor e Forma:SolidPeso molecular:615.67(-)SHIN2
<p>'(-)SHIN2 isomer of (+)SHIN2, an SHMT inhibitor with antileukemic properties; enhances Methotrexate's effect in vivo.</p>Fórmula:C23H26N4O3Cor e Forma:SolidPeso molecular:406.48NYX-2925
CAS:NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.Fórmula:C14H23N3O4Cor e Forma:SolidPeso molecular:297.35ICA-121431
CAS:<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Fórmula:C23H19N3O3S2Pureza:98.06%Cor e Forma:SolidPeso molecular:449.55RP101442
CAS:RP101442: Ozanimod metabolite, selective S1PR1 agonist, EC50: 2.6 nM (S1PR1), 171 nM (S1PR5).Fórmula:C23H22N4O3Cor e Forma:SolidPeso molecular:402.45RP101988
RP101988, a potent Ozanimod metabolite, selectively targets S1PR1 with EC50 of 0.19 nM and S1PR5 at 32.8 nM.Fórmula:C23H22N4O4Cor e Forma:SolidPeso molecular:418.45C-di-IMP
CAS:Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.Fórmula:C20H22N8O14P2Cor e Forma:SolidPeso molecular:660.38MEK-IN-5
CAS:<p>MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.</p>Fórmula:C29H27FN4O10S2Cor e Forma:SolidPeso molecular:674.67BLK-IN-2
CAS:<p>BLK-IN-2为一种高效、选择性且不可逆的B-淋巴酪氨酸激酶(BLK)抑制剂，具有5.9 nM的IC50值。该化合物亦能抑制BTK，其IC50值为202.0 nM。BLK-IN-2在多种淋巴瘤细胞中展现出显著的抗增殖作用。</p>Fórmula:C39H41N9O3Cor e Forma:SolidPeso molecular:683.8Zn(BQTC)
CAS:Zn(BQTC) inhibits mtDNA and nDNA, damages mitochondria/nuclei, triggers apoptosis, and targets A549R cancer cells.Fórmula:C30H36Cl2N5O3ZnPureza:98%Cor e Forma:SolidPeso molecular:650.92UniPR505
CAS:<p>UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.</p>Fórmula:C39H57N3O5Pureza:98.23%Cor e Forma:SolidPeso molecular:647.89UR-MB108
CAS:UR-MB108 is a potent and selective inhibitor of ABCG2 (BCRP), displaying an IC50 value of 79 nM, and exhibits stability in blood plasma.Fórmula:C40H38N6O4Cor e Forma:SolidPeso molecular:666.77Kinetin riboside
CAS:Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)Fórmula:C15H17N5O5Pureza:98.17%Cor e Forma:White SolidPeso molecular:347.33
