CAS 100016-62-4: thyrocalcitonin
Description:Thyrocalcitonin, also known as calcitonin, is a peptide hormone produced primarily by the parafollicular cells (C cells) of the thyroid gland. It plays a crucial role in calcium homeostasis by lowering blood calcium levels, primarily through its action on bone and kidney. The hormone inhibits osteoclast activity, which reduces bone resorption, and promotes renal excretion of calcium. Thyrocalcitonin is composed of 32 amino acids in its human form and exhibits a molecular weight characteristic of peptide hormones. It is often used therapeutically in conditions such as osteoporosis and Paget's disease, where it helps to mitigate excessive bone loss. The CAS number 100016-62-4 specifically identifies the synthetic form of calcitonin, which can be derived from various sources, including salmon, which has a higher potency than human calcitonin. In terms of stability, calcitonin is sensitive to heat and pH changes, necessitating careful handling and storage conditions to maintain its efficacy.
Formula:C145H240N42O46S2
- Synonyms:
- Calcitonin (chicken)
- H-Cys-Ala-Ser-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Disulfide bond)
Brand | Product data | Purity | Price range | Estimated delivery |
---|---|---|---|---|
![]() | Calcitonin, chicken REF: 3D-FC73304CAS: 100016-62-4 | Min. 95% | - - - | Discontinued product |
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Calcitonin, chicken
Ref: 3D-FC73304
1mg | Discontinued | Request information | |
2mg | Discontinued | Request information | |
100µg | Discontinued | Request information | |
250µg | Discontinued | Request information | |
500µg | Discontinued | Request information |