CAS 1004990-28-6: PF-AKT400

Description: PF-AKT400, with the CAS number 1004990-28-6, is a chemical compound that functions primarily as a selective inhibitor of the AKT signaling pathway, which is crucial in various cellular processes including metabolism, proliferation, and survival. This compound is often studied in the context of cancer research, as aberrant AKT activity is associated with tumor growth and resistance to therapy. PF-AKT400 exhibits high specificity for AKT isoforms, making it a valuable tool for investigating the role of AKT in disease mechanisms and for potential therapeutic applications. Its chemical structure includes functional groups that facilitate its interaction with the target protein, enhancing its efficacy. Additionally, PF-AKT400's pharmacokinetic properties, such as solubility and stability, are important for its bioavailability and overall effectiveness in biological systems. As with many research compounds, safety and handling precautions are essential, and its use is typically confined to laboratory settings under controlled conditions.

PF-AKT400

CAS: 1004990-28-6

PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.

• Formula: C₂₀H₂₂F₂N₆O
• Purity: 98.21%
• Color and Shape: Solid
• Molecular weight: 400.43

(S)-N-[[3-Amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamide

CAS: 1004990-28-6

(S)-N-[[3-Amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamide is a prodrug that is converted to the active form by esterases in the …

• Formula: C₂₀H₂₂F₂N₆O
• Purity: Min. 95%
• Molecular weight: 400.43 g/mol