CAS 102130-84-7: Nemadectin

Description: Nemadectin is a macrocyclic lactone compound that belongs to the class of anthelmintics, primarily used for its efficacy against parasitic infections in various organisms, including nematodes and arthropods. It is derived from the fermentation of certain soil bacteria, specifically from the genus Streptomyces. The compound exhibits a broad spectrum of activity, making it valuable in agricultural and veterinary applications. Nemadectin functions by interfering with the neuromuscular transmission in parasites, leading to paralysis and eventual death. Its chemical structure features a large lactone ring, which is characteristic of many compounds in the avermectin family. The substance is typically administered in formulations that enhance its bioavailability and effectiveness. Safety profiles indicate that it has low toxicity to non-target organisms, making it a preferred choice in integrated pest management strategies. However, as with any chemical agent, proper handling and application guidelines should be followed to minimize environmental impact and resistance development in target populations.

Formula: C₃₆H₅₂O₈

InChI: InChI=1/C36H52O8/c1-20(2)13-24(6)32-25(7)30(37)18-35(44-32)17-28-16-27(43-35)12-11-22(4)14-21(3)9-8-10-26-19-41-33-31(38)23(5)15-29(34(39)42-28)36(26,33)40/h8-11,13,15,20-21,25,27-33,37-38,40H,12,14,16-19H2,1-7H3/b9-8+,22-11+,24-13+,26-10+/t21-,25-,27+,28-,29-,30-,31+,32+,33+,35-,36+/m0/s1

Synonyms:

• Nemadectin [USAN:INN]
• (2aE,4E,4'S,5'S,6R,6'S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-((E)-1,3-Dimethyl-1-butenyl)-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-4',20,20b-trihydroxy-5',6,8,19-tetramethylspiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-17-one
• (6R,23S,25S)-5-O-Demethyl-28-deoxy-25-((E)-1,3-dimethyl-1-butenyl)-6,28-epoxy-23-hydroxymilbemycin B
• Cl 287,088
• F28249alpha
• Milbemycin B, 5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-hydroxy-, (6R,23S,25S(E))-
• Nemadectina
• Nemadectina [INN-Spanish]
• Nemadectine
• Nemadectine [INN-French]
• Nemadectinum
• Nemadectinum [INN-Latin]
• Unii-1Y8Vj1G3Ty

Nemadectin

CAS: 102130-84-7

• Formula: C₃₆H₅₂O₈
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 612.7932800000001

Nemadectin

CAS: 102130-84-7

• Formula: C₃₆H₅₂O₈
• Color and Shape: White To Off-White Solid
• Molecular weight: 612.80

Nemadectin

CAS: 102130-84-7

• Formula: C₃₆H₅₂O₈
• Color and Shape: White
• Molecular weight: 612.793

(6R,23S,25S)-5-O-Demethyl-28-Deoxy-25-((E)-1,3-Dimethyl-1-Butenyl)-6,28-Epoxy-23-Hydroxymilbemycin B

CAS: 102130-84-7

Nemadectin is a macrocyclic lactone that is active against endoparasites of animals. It is used …

• Formula: C₃₆H₅₂O₈
• Purity: Min. 95%
• Molecular weight: 612.79 g/mol