CAS 103026-83-1: Dehydro Nisoldipine

Description: Dehydro Nisoldipine is a chemical compound that belongs to the class of dihydropyridine calcium channel blockers, primarily used in the treatment of hypertension and angina. It is characterized by its ability to selectively inhibit calcium influx through L-type calcium channels, leading to vasodilation and reduced blood pressure. The compound is typically administered in its racemic form and exhibits a high degree of lipophilicity, which enhances its absorption and bioavailability. Dehydro Nisoldipine has a relatively long half-life, allowing for once-daily dosing in clinical settings. Its pharmacological profile includes not only antihypertensive effects but also potential cardioprotective benefits. The compound is generally well-tolerated, though it may cause side effects such as peripheral edema, headache, and flushing. As with other calcium channel blockers, caution is advised in patients with certain cardiovascular conditions. Overall, Dehydro Nisoldipine represents an important therapeutic option in the management of cardiovascular diseases.

Formula: C₂₀H₂₂N₂O₆

Synonyms:

• 2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(2-Methylpropyl) Ester

Nisoldipine USP Related Compound D (Dehydro Nisoldipine)

CAS: 103026-83-1

• Formula: C₂₀H₂₂N₂O₆
• Molecular weight: 386.41

Nisoldipine USP Related Compound D-d6 (Dehydro Nisoldipine-d6)

CAS: 103026-83-1

• Formula: C₂₀H₁₆D₆N₂O₆
• Molecular weight: 392.44

Dehydro Nisoldipine

CAS: 103026-83-1

Applications A metabolite of Nisoldipine (N489125). References Grossi, P., et al.: Xenobiotica, 22, 899 (1992), …

• Formula: C₂₀H₂₂N₂O₆
• Color and Shape: Neat
• Molecular weight: 386.40

Nisoldipine Related Compound D (3-Isobutyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate) (DISCONTINUED)

CAS: 103026-83-1

Compounds containing an unfused pyridine ring in the structure, nesoi

• Formula: C₂₀H₂₂N₂O₆
• Color and Shape: Pale Yellow Solid
• Molecular weight: 386.14779

3-Isobutyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate

CAS: 103026-83-1

• Purity: 98%
• Molecular weight: 386.40399169921875

Dehydro nisoldipine

CAS: 103026-83-1

Dehydro nisoldipine is a drug that belongs to the pyridinoid class of drugs. It has …

• Formula: C₂₀H₂₂N₂O₆
• Purity: Min. 95%
• Molecular weight: 386.4 g/mol