CAS 104195-61-1: Rubitecan

Description: Rubitecan, with the CAS number 104195-61-1, is a synthetic compound primarily studied for its potential use in cancer therapy. It belongs to the class of camptothecin derivatives, which are known for their mechanism of action as topoisomerase I inhibitors. This inhibition disrupts DNA replication and transcription, leading to cancer cell death. Rubitecan exhibits a unique chemical structure that contributes to its pharmacological properties, including its solubility and stability. The compound has been evaluated in various preclinical and clinical studies, demonstrating activity against a range of tumor types. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for understanding its therapeutic potential and optimizing dosing regimens. Additionally, like many anticancer agents, Rubitecan may have associated side effects, which necessitate careful monitoring during treatment. Ongoing research aims to further elucidate its efficacy and safety profile, as well as to explore combination therapies that may enhance its anticancer effects.

Formula: C₂₀H₁₅N₃O₆

InChI: InChI=1/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1

Synonyms:

• 9-Nitrocellulose camptothecine
• (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 4-ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (4R)-4-ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

10-Nitro-camptothecin

CAS: 104195-61-1

10-Nitro-camptothecin is a natural product

• Formula: C₂₀H₁₅N₃O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 393.35

10-Nitro Camptothecin

CAS: 104195-61-1

• Formula: C₂₀H₁₅N₃O₆
• Purity: 95%~99%
• Molecular weight: 393.355