CAS: 1051375-16-6 - Dolutegravir

Formula: C₂₀H₁₉F₂N₃O₅

InChI: InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1

InChI key: InChIKey=RHWKPHLQXYSBKR-BMIGLBTASA-N

SMILES: O=C(NCC1=CC=C(F)C=C1F)C2=CN3C(C(=O)N4C(OCCC4C)C3)=C(O)C2=O

Synonyms:

• (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
• (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
• (4R,9aS)-5-Hydroxy-4-methyl-6,10-dioxo-3,4,6,9,9a,10-hexahydro-2H-1-oxa-4a,8a-diaza-anthracene-7-carboxylic acid 2,4-difluoro-benylamide
• 2H-Pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
• Dolutegravir free acid
• Gsk 1349572
• Gsk1349572
• S/Gsk1349572
• Soltegravir
• Tivicay

Dolutegravir-d5

CAS: 1051375-16-6

• Formula: C₂₀H₁₄D₅F₂N₃O₅
• Color and Shape: Off-White Solid
• Molecular weight: 424.42

Dolutegravir Sodium Salt

CAS: 1051375-16-61051375-19-9

• Formula: C₂₀H₁₈F₂N₃O₅·Na
• Color and Shape: Pale Yellow Solid
• Molecular weight: 418.38 22.99

Dolutegravir

CAS: 1051375-16-6

• Formula: C₂₀H₁₉F₂N₃O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 419.38

Dolutegravir

CAS: 1051375-16-6

Dolutegravir (GSK1349572), HIV integrase inhibitor with IC50 of 2.7 nM, partly effective against some raltegravir-resistant …

• Formula: C₂₀H₁₉F₂N₃O₅
• Purity: 99.05% - 99.08%
• Color and Shape: White To Pale Yellow Solid
• Molecular weight: 419.38

Dolutegravir (0.1 mg/mL in Methanol)

CAS: 1051375-16-6

• Formula: C₂₀H₁₉F₂N₃O₅
• Color and Shape: Colourless
• Molecular weight: 419.38

Dolutegravir-d4

CAS: 1051375-16-6

Applications Isotope labelled Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is …

• Formula: C₂₀H₁₅D₄F₂N₃O₅
• Purity: >80%
• Color and Shape: Neat
• Molecular weight: 423.40

Dolutegravir

CAS: 1051375-16-6

Applications Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in …

• Formula: C₂₀H₁₉F₂N₃O₅
• Color and Shape: Neat
• Molecular weight: 419.38

Dolutegravir

CAS: 1051375-16-6

Dolutegravir is an HIV-1 integrase inhibitor. Dolutegravir is used in the treatment of HIV-1 infections …

• Formula: C₂₀H₁₉F₂N₃O₅
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 419.40 g/mol