CAS 1062368-24-4: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

Description: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, identified by its CAS number 1062368-24-4, is a synthetic organic compound that belongs to a class of heterocyclic compounds. This substance features a complex molecular structure that includes a quinoline core fused with a pyrazolo-pyrimidine moiety, along with a piperazine substituent. The presence of these heterocycles suggests potential biological activity, particularly in medicinal chemistry, where such compounds are often explored for their pharmacological properties. The piperazine group may enhance solubility and bioavailability, making it a candidate for drug development. The compound's characteristics, including its molecular weight, solubility, and stability, would be influenced by its specific functional groups and overall structure. Additionally, its potential applications could span various therapeutic areas, including oncology and neurology, depending on its mechanism of action and interaction with biological targets. Further studies would be necessary to elucidate its full profile, including toxicity and efficacy in biological systems.

Formula: C₂₅H₂₂N₆

InChI: InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2

InChI key: InChIKey=CDOVNWNANFFLFJ-UHFFFAOYSA-N

SMILES: N=1C=CC(C=2C=NN3C=C(C=NC23)C=4C=CC(=CC4)N5CCNCC5)=C6C=CC=CC16

Synonyms:

• 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
• 6-(4-(2-(Piperidin-1-Yl)Ethoxy)Phenyl)-3-(Pyridin-4-Yl)Pyrazolo[1,5-A]Pyrimidine
• Dm 3189
• Ldn 193189
• Quinoline, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-

6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine

CAS: 1062368-24-4

• Formula: C₂₅H₂₂N₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 406.4824

LDN193189

CAS: 1062368-24-4

LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.

• Formula: C₂₅H₂₂N₆
• Purity: 98% - 99.86%
• Color and Shape: Solid
• Molecular weight: 406.48

LDN 193189-d8

CAS: 1062368-24-4

• Formula: C₂₅D₈H₁₄N₆
• Color and Shape: Neat
• Molecular weight: 414.532

LDN 193189

CAS: 1062368-24-4

• Formula: C₂₅H₂₂N₆
• Color and Shape: Neat
• Molecular weight: 406.482

LDN 193189

CAS: 1062368-24-4

Inhibitor of ALK1, ALK2, ALK3 and ALK6 kinases and bone morphogenetic protein (BMP) pathway. LDN …

• Formula: C₂₅H₂₂N₆
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 406.48 g/mol