
CAS 107007-95-4
:GRANISETRON IMPURITY B
Description:
Granisetron Impurity B, with the CAS number 107007-95-4, is a chemical compound associated with the synthesis of granisetron, a medication primarily used as an antiemetic to prevent nausea and vomiting. As an impurity, it may arise during the manufacturing process of granisetron and is typically characterized by its specific molecular structure and properties. While detailed information on its physical and chemical properties may be limited, impurities like Granisetron Impurity B are often assessed for their potential impact on the efficacy and safety of the final pharmaceutical product. In general, impurities can affect the stability, solubility, and overall quality of the drug formulation. Regulatory agencies require thorough characterization and quantification of such impurities to ensure compliance with safety standards. Analytical techniques such as chromatography and mass spectrometry are commonly employed to identify and quantify impurities in pharmaceutical substances. Understanding the characteristics of impurities is crucial for maintaining the integrity of drug development and ensuring patient safety.
Formula:C17H22N4O
Synonyms:- 1-Desmethyl Granisetron (Granisetron Impurity B)
- endo-N-(9-Methyl-9-azabicyclo[3.3.1]non-3-yl)-1H-indazole-3-carboxamide
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 7 products.
Granisetron Related Compound B (N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C17H22N4OColor and Shape:Off-White White PowderMolecular weight:298.17936Granisetron EP Impurity B (Granisetron USP Related Compound B)
CAS:Formula:C17H22N4OColor and Shape:White To Off-White SolidMolecular weight:298.39N-[(1R,3r,5S)-9-Methyl-9-azabicyclo-[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
CAS:Color and Shape:Neat1-Desmethyl Granisetron (Granisetron Impurity B)
CAS:Controlled Product<p>Impurity Granisetron USP Related Compound B<br>Applications Granisetron Impurity B having 5-HT antagonist activity.<br>References Bermudez, J., et al.: J. Med. Chem., 33, 1924 (1990), Clarke, S. E., et al.: Xenobiotica, 24, 1119 (1994),<br></p>Formula:C17H22N4OColor and Shape:NeatMolecular weight:298.38N-((1R,3r,5S)-9-Methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide (Granisetron Impurity)
CAS:Purity:98%Molecular weight:298.181-Desmethyl granisetron
CAS:Controlled Product1-Desmethyl granisetron is an impurity found in the synthesis of granisetron hydrochloride. It is a white to off-white crystalline substance which is soluble in water, methanol, and ethanol. 1-Desmethyl granisetron has a molecular weight of 328.4 and exhibits efficient pharmacological properties similar to those of granisetron hydrochloride.Formula:C17H22N4OPurity:Min. 95%Molecular weight:298.38 g/mol







