CAS 107667-60-7: Polaprezinc
Description:Polaprezinc is a coordination compound that consists of zinc and the amino acid L-carnosine. It is primarily used for its gastroprotective properties, particularly in the treatment of gastric ulcers and other gastrointestinal disorders. The compound exhibits antioxidant activity, which helps in reducing oxidative stress in the gastric mucosa. Polaprezinc promotes the healing of gastric tissues by enhancing the production of mucin, a protective gel-like substance that lines the stomach, thereby contributing to the maintenance of the gastric barrier. Additionally, it has anti-inflammatory properties that can further aid in the healing process. Polaprezinc is typically administered in oral form and is well-tolerated, with a favorable safety profile. Its unique formulation allows for improved bioavailability of zinc, which is essential for various biological functions, including immune response and tissue repair. Overall, Polaprezinc serves as an effective therapeutic agent in managing gastrointestinal health, particularly in conditions associated with mucosal injury.
Formula:C9H12N4O3Zn
InChI:InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/m0./s1
InChI key:InChIKey=IGXZLYMCFZHNKW-FJXQXJEOSA-L
SMILES:O=C1[O-][Zn+2]2[N-](C(=O)CC[NH2]2)C1CC3=CN=CN3
- Synonyms:
- <span class="text-smallcaps">L</span>-Histidine, N-β-alanyl-, zinc complex
- Histidine, Β-Alanyl-, Zinc Salt (1:1)
- Promac
- Promac (antiulcer agent)
- Z 103
- Zinc <span class="text-smallcaps">L</span>-carnosine
- Zinc Carnosine
- Zinc, [N-β-alanyl-<span class="text-smallcaps">L</span>-histidinato(2-)-N,N<sup>N</sup>,O<sup>α</sup>]-
- Zinc, [β-alanyl-κN-<span class="text-smallcaps">L</span>-histidinato(2-)-κN,κO]-
- zinc 2-[(3-azanidyl-1-oxido-propylidene)amino]-3-(3H-imidazol-4-yl)propanoate
- See more synonyms
- β-Alanyl-<span class="text-smallcaps">L</span>-histidinato zinc
- L-Histidine, N-β-alanyl-, zinc complex
- Zinc L-carnosine
- Zinc, [β-alanyl-κN-L-histidinato(2-)-κN,κO]-
- Zinc, [N-β-alanyl-L-histidinato(2-)-N,NN,Oα]-
