CAS 1092351-67-1: Torkinib

Description: Torkinib, with the CAS number 1092351-67-1, is a small molecule that functions primarily as a selective inhibitor of certain kinases, particularly those involved in signaling pathways related to cancer cell proliferation and survival. It is characterized by its ability to interfere with the activity of specific enzymes, thereby modulating cellular processes such as growth, differentiation, and apoptosis. Torkinib has been studied for its potential therapeutic applications in oncology, particularly in the treatment of various types of tumors that exhibit aberrant kinase activity. The compound's chemical structure typically includes functional groups that enhance its binding affinity to target proteins, contributing to its efficacy as an inhibitor. Additionally, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are crucial for determining its suitability for clinical use. As with many targeted therapies, ongoing research aims to elucidate its full spectrum of biological effects and potential side effects, ensuring a comprehensive understanding of its role in cancer treatment.

Formula: C₁₆H₁₆N₆O

InChI: InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,20,23H,1-2H3,(H2,17,18,19)

InChI key: InChIKey=MFAQYJIYDMLAIM-UHFFFAOYSA-N

SMILES: OC=1C=CC=2NC(=CC2C1)C3=NN(C=4N=CN=C(N)C34)C(C)C

Synonyms:

• 1H-Indol-5-ol, 2-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-
• 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
• 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
• Pp242
• Torkinib
• PP 242

PP242

CAS: 1092351-67-1

• Formula: C₁₆H₁₆N₆O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 308.3378

Torkinib

CAS: 1092351-67-1

Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). …

• Formula: C₁₆H₁₆N₆O
• Purity: 99.23%
• Color and Shape: Solid
• Molecular weight: 308.34

PP242

CAS: 1092351-67-1

• Purity: ≥ 95.0%
• Color and Shape: White to off-white solid

PP242

CAS: 1092351-67-1

• Formula: C₁₆H₁₆N₆O
• Purity: 99.60% (Typical Value in Batch COA)
• Color and Shape: yellow solid
• Molecular weight: 308.34g/mol

Torkinib (PP242)

CAS: 1092351-67-1

Torkinib is a matrix-effect inhibitor that inhibits the activity of the mTOR protein. It was …

• Formula: C₁₆H₁₆N₆O
• Purity: Min. 95%
• Molecular weight: 308.34 g/mol