CAS 109292-46-8

H-Arg-Gly-Asp-Cys-OH

Description:

H-Arg-Gly-Asp-Cys-OH, also known as a peptide, is a synthetic compound that consists of a sequence of amino acids: arginine (Arg), glycine (Gly), aspartic acid (Asp), and cysteine (Cys). This peptide is notable for its role in biological processes, particularly in cell adhesion and signaling due to the presence of the RGD (arginine-glycine-aspartic acid) motif, which is recognized by integrin receptors on cell surfaces. The cysteine residue allows for the formation of disulfide bonds, which can stabilize the peptide's structure and influence its biological activity. The compound is often studied in the context of drug delivery, tissue engineering, and as a potential therapeutic agent due to its ability to interact with various cell types. Its CAS number, 109292-46-8, uniquely identifies this specific peptide in chemical databases. Overall, H-Arg-Gly-Asp-Cys-OH exemplifies the importance of peptide sequences in biochemistry and their applications in medical and biotechnological fields.

Formula: C₁₅H₂₇N₇O₇S

H-Arg-Gly-Asp-Cys-OH

CAS: 109292-46-8

Surfaces modified with RGDC were shown to be effective for osteoblast binding and proliferation. RGDC binds via its sulfhydryl moiety to gold particles and gold-coated implants increasing the biocompatibility of the latter. The surface of titanium implants has to be modified beforehand to allow covalent S binding.

Formula: C₁₅H₂₇N₇O₇S

Purity: > 97%

Color and Shape: White Crystalline Powder

Molecular weight: 449.49

Ref: 01-4030602

H-ARG-GLY-ASP-CYS-OH

CAS: 109292-46-8

Formula: C₁₅H₂₇N₇O₇S

Purity: 98%

Molecular weight: 449.4826

Ref: IN-DA008RSF

Arg-Gly-Asp-Cys

CAS: 109292-46-8

Arg-Gly-Asp-Cys is the binding motif of fibronectin and cell adhesion molecules, which can inhibit platelet aggregation and fibrinogen binding.

Formula: C₁₅H₂₇N₇O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 449.48

Ref: TM-TP1447

H-Arg-Gly-Asp-Cys-OH

CAS: 109292-46-8

H-Arg-Gly-Asp-Cys-OH is a biomimetic amino acid that possesses the same three-dimensional structure as the amino acid sequence found in the human epidermal growth factor receptor 2 (HER2). This compound has been shown to inhibit the activity of enzymes, such as kinases, which are involved in cancer cell division. It also can be used to target and destroy cancer cells using gene therapy. H-Arg-Gly-Asp-Cys-OH binds to messenger RNA and inhibits its translation into protein, which may lead to cell death. H-Arg-Gly-Asp-Cys -OH has been shown to bind specifically with HER2 receptors on breast cancer cells and promote their destruction by inducing apoptosis.

Formula: C₁₅H₂₇N₇O₇S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 449.48 g/mol

Ref: 3D-FA108900