CAS 1095-90-5: Methadone hydrochloride
Description:Methadone hydrochloride is a synthetic opioid used primarily in the treatment of opioid addiction and for pain management. It is a white to off-white crystalline powder that is soluble in water and alcohol, which facilitates its administration in various forms, including oral and injectable routes. The substance acts as a long-acting agonist at the mu-opioid receptors in the central nervous system, providing analgesic effects while also helping to mitigate withdrawal symptoms in individuals dependent on other opioids. Methadone has a relatively long half-life, allowing for once-daily dosing in maintenance therapy. Its pharmacokinetics can be influenced by factors such as metabolism, age, and concurrent medications, necessitating careful monitoring to avoid potential toxicity or overdose. Additionally, methadone can cause side effects typical of opioids, including respiratory depression, sedation, and constipation. Due to its potential for abuse and dependence, methadone is classified as a controlled substance in many jurisdictions, and its use is typically regulated within specialized treatment programs.
Formula:C21H27NO·ClH
InChI:InChI=1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H
InChI key:InChIKey=FJQXCDYVZAHXNS-UHFFFAOYSA-N
SMILES:Cl.O=C(CC)C(C=1C=CC=CC1)(C=2C=CC=CC2)CC(N(C)C)C
- Synonyms:
- (±)-Methodone hydrochloride
- 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, hydrochloride
- 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, hydrochloride (1:1)
- 4,4-Diphenyl-6-dimethylamino-3-heptanone hydrochloride
- 6-(Dimethylamino)-4,4-Diphenylheptan-3-One
- 6-(Dimethylamino)-4,4-Diphenylheptan-3-One Dihydrochloride
- 6-(Dimethylamino)-4,4-Diphenylheptan-3-One Hydrochloride (1:1)
- 6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride
- <span class="text-smallcaps">D</smallcap>,<smallcap>L</span>-Methadone hydrochloride
- <span class="text-smallcaps">DL</span>-Methadone hydrochloride
- See more synonyms
- Adanon
- Adanon hydrochloride
- Adolan
- Algidon
- Algolysin
- Amidon
- An 148
- Butalgin
- Depridol
- Diaminon hydrochloride
- Dolofin hydrochloride
- Dolophin hydrochloride
- Dolophine
- Fenadon
- Fenadone
- Heptadon
- Hoechst 10820
- Ketalgin
- Ketalgin hydrochloride
- Mecodin
- Mephenon
- Methadone HCl
- Methadone Hydrochloride {D.D.}
- Methadose
- Miadone
- Moheptan
- NSC 19600
- Phenadone hydrochloride
- Polamidon
- Racemic methadone hydrochloride
- dl-6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride
- dl-Methadone hydrochloride
- Methadone hydrochloride
