CAS 11034-93-8: Globotetraosylceramide

Description: Globotetraosylceramide, also known as Gb4 or lactosylceramide, is a glycosphingolipid characterized by its structure, which consists of a ceramide backbone linked to a carbohydrate moiety containing four sugar units. This compound plays a significant role in cell membrane structure and function, particularly in the context of cell signaling and recognition processes. It is primarily found in the membranes of certain cells, including those in the immune system and the nervous system. Globotetraosylceramide is involved in various biological functions, including cell adhesion, differentiation, and the modulation of immune responses. Its presence is also associated with certain pathological conditions, such as Gaucher's disease and other lysosomal storage disorders, where its accumulation can lead to cellular dysfunction. The compound is of interest in biomedical research, particularly in studies related to cancer, neurodegenerative diseases, and the development of therapeutic agents targeting glycosphingolipid metabolism. Understanding its characteristics and functions can provide insights into both normal physiological processes and disease mechanisms.

Formula: Unspecified

InChI: InChI=1/C56H102N2O23/c1-4-6-8-10-12-14-15-16-17-19-20-22-24-26-35(64)34(58-40(65)27-25-23-21-18-13-11-9-7-5-2)32-74-54-47(71)45(69)50(38(30-61)77-54)79-55-48(72)46(70)51(39(31-62)78-55)80-56-49(73)52(43(67)37(29-60)76-56)81-53-41(57-33(3)63)44(68)42(66)36(28-59)75-53/h24,26,34-39,41-56,59-62,64,66-73H,4-23,25,27-32H2,1-3H3,(H,57,63)(H,58,65)/b26-24+/t34-,35+,36+,37+,38+,39+,41+,42-,43-,44+,45+,46+,47?,48+,49+,50+,51-,52-,53-,54+,55-,56+/m0/s1

Synonyms:

• CQH (globoside)
• Ceramide, 1-O-[O-2-(acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-(1→3)-O-α-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-β-<smallcap>D</span>-glucopyranosyl]-
• Cytolipin K
• Galnac-1-3-gal-1-4-gal-1-4-glc-cer
• Ganglioside GL 4
• Ganglioside Gb₄
• Gb4 Globoside
• Gb4 Globotetraosyl ceramide
• Gb4Cer
• Gb₄
• Gb₄Cer
• Gbose4Cer
• Globo-N-tetraosylceramide
• Globoside (human erythrocytes)
• Globoside GL-4
• Globoside Gb 4
• Globoside I
• Globosidic acid
• Globotetraosyl ceramide
• Globotetraosylceramide
• Parvovirus B19 receptor
• Slt-iiv receptor
• Tetrahexosylceramide
• VT2vp1 Receptor
• Ceramide, 1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-

Globotetraosylceramides (porcine RBC)

CAS: 11034-93-8

Globotetraosylceramides: Neutral glycosphingolipids in human red cells, receptor for Shiga toxins/pierisin-1/B19 virus, aid tooth enamel …

• Formula: C₆₈H₁₂₆N₂O₂₃(fortetracosanoyl)
• Color and Shape: Liquid
• Molecular weight: 1339.7

Globoside

CAS: 11034-93-8

Globosides (GL4, Gb4, globotetrahexosyl Ceramide)

CAS: 11034-93-8

• Formula: Unspecified
• Purity: >98%
• Color and Shape: Solid

Globoside

CAS: 11034-93-8

Globoside is the most abundant neutral glycolipid in the erythrocyte membrane.

• Formula: C₅₆H₁₀₂N₂O₂₃
• Purity: Min. 90%
• Color and Shape: White Powder
• Molecular weight: 1,171.41 g/mol