CAS 111278-01-4: anguinomycin A

Description: Anguinomycin A is a naturally occurring anthracycline antibiotic that exhibits notable antitumor properties. It is derived from the fermentation of specific Streptomyces species. The compound is characterized by its complex polycyclic structure, which includes a sugar moiety that enhances its biological activity. Anguinomycin A functions primarily by intercalating into DNA, disrupting the replication process, and ultimately leading to cell death, making it a subject of interest in cancer research. Its mechanism of action is similar to that of other anthracyclines, such as doxorubicin, but it may exhibit a distinct profile in terms of efficacy and toxicity. The compound has been studied for its potential therapeutic applications, particularly in the treatment of various malignancies. However, like many antibiotics, it may also present challenges related to resistance and side effects. Ongoing research aims to better understand its pharmacological properties and to explore its potential in combination therapies for enhanced anticancer efficacy.

Formula: C₃₁H₄₄O₆

InChI: InChI=1/C31H44O6/c1-20(16-22(3)14-15-27-12-9-13-29(34)37-27)10-8-11-21(2)17-24(5)30(35)26(7)31(36)25(6)18-23(4)19-28(32)33/h8-9,11,13-17,19-20,24-27,31,36H,10,12,18H2,1-7H3,(H,32,33)/b11-8+,15-14+,21-17+,22-16+,23-19+

Synonyms:

• 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-
• (2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-19-(6-oxo-3,6-dihydro-2H-pyran-2-yl)nonadeca-2,10,12,16,18-pentaenoic acid
• Anguinomycin A

Anguinomycin A

CAS: 111278-01-4

Anguinomycin A, an antibiotic from Streptomyces, is like leptomycin B, kills mouse leukemia cells, and …

• Formula: C₃₁H₄₄O₆
• Color and Shape: Solid
• Molecular weight: 512.687

Anguinomycin A

CAS: 111278-01-4

• Formula: C₃₁H₄₄O₆
• Purity: (HPLC) ≥ 95.0%
• Color and Shape: Light yellow film
• Molecular weight: 512.7