Description:(D-LEU6)-LHRH (1-8), also known as D-Leucine 6-Luteinizing Hormone-Releasing Hormone, is a synthetic analog of the naturally occurring gonadotropin-releasing hormone (GnRH). This peptide is characterized by its modification at the sixth position, where the natural leucine is replaced with D-leucine, enhancing its stability and resistance to enzymatic degradation. The structure consists of eight amino acids, which are crucial for its biological activity, primarily in stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This compound is often utilized in research and clinical settings for its potential applications in reproductive health and hormone regulation. Its pharmacological properties include a longer half-life compared to native GnRH, making it a valuable tool in studies related to hormone therapies and endocrine disorders. Additionally, it may exhibit varying affinities for GnRH receptors, influencing its efficacy in different biological contexts.
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