CAS 1131-64-2: Debrisoquine

Description: Debrisoquine, with the CAS number 1131-64-2, is a chemical compound primarily known for its role as an antihypertensive agent. It belongs to the class of compounds known as sympatholytics, which work by inhibiting the sympathetic nervous system's activity, leading to a reduction in blood pressure. Debrisoquine is characterized by its ability to selectively block the release of norepinephrine, thereby decreasing peripheral vascular resistance. This compound is also notable for its genetic polymorphism in metabolism, where individuals may exhibit varying responses to the drug based on their genetic makeup, particularly involving the CYP2D6 enzyme. In terms of physical properties, Debrisoquine is typically a white to off-white crystalline powder, soluble in water and organic solvents. Its pharmacokinetics and pharmacodynamics have made it a subject of study in understanding drug metabolism and the implications of genetic variability in drug response. Overall, Debrisoquine serves as an important example in pharmacology, illustrating the intersection of chemistry, genetics, and therapeutic efficacy.

Formula: C₁₀H₁₃N₃

InChI: InChI=1S/C10H13N3/c11-10(12)13-6-5-8-3-1-2-4-9(8)7-13/h1-4H,5-7H2,(H3,11,12)

InChI key: InChIKey=JWPGJSVJDAJRLW-UHFFFAOYSA-N

SMILES: N=C(N)N1CC=2C=CC=CC2CC1

Synonyms:

• 1,2,3,4-Tetrahydroisoquinoline-2-carboximidamide
• 2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro-
• 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-
• 2-Amidino-1,2,3,4-tetrahydroisoquinoline
• 3,4-Dihydro-1H-isoquinoline-2-carboxamidine
• 3,4-Dihydro-2(1H)-isoquinolinecarboxamidine
• 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide
• 3,4-dihydroisoquinoline-2(1H)-carboximidamide
• Debrisochin
• Debrisochinum
• Debrisoquin
• Debrisoquina
• Debrisoquina [INN-Spanish]
• Debrisoquine [INN:BAN]
• Debrisoquinum
• Debrisoquinum [INN-Latin]
• Isocaramidine
• Unii-X31Cdk040E
• Debrisoquine
• Debrisoquine

Debrisoquin

CAS: 1131-64-2

Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitor that prevents SARS-CoV-2 from entering human lung cells through …

• Formula: C₁₀H₁₃N₃
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 175.23

3,4-Dihydro-1H-isoquinoline-2-carboxamidine

CAS: 1131-64-2

3,4-Dihydro-1H-isoquinoline-2-carboxamidine (DHICA) is an enzyme inhibitor that can be used to treat infectious diseases. It …

• Formula: C₁₀H₁₃N₃
• Purity: Min. 95%
• Molecular weight: 175.23 g/mol