CAS 113981-44-5: Cefozopran monohydrochloride

Description: Cefozopran monohydrochloride is a synthetic antibiotic belonging to the cephalosporin class, which is characterized by its beta-lactam structure. This compound is primarily used for its antibacterial properties, effective against a range of Gram-positive and Gram-negative bacteria. It exhibits a broad spectrum of activity, making it suitable for treating various infections. The monohydrochloride form indicates that it is a hydrochloride salt, which enhances its solubility in water, facilitating its administration. Cefozopran is known for its stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many antibiotics. Its pharmacokinetic profile typically includes good absorption and distribution in body tissues, contributing to its efficacy in clinical settings. As with other cephalosporins, potential side effects may include allergic reactions, gastrointestinal disturbances, and effects on renal function. Overall, Cefozopran monohydrochloride represents an important option in the arsenal of antibiotics used to combat bacterial infections.

Formula: C₁₉H₁₈N₉O₅S₂·Cl

InChI: InChI=1S/C19H17N9O5S2.ClH/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27;/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32);1H/b24-11-;/t12-,17-;/m1./s1

InChI key: InChIKey=NTJHUKMPVIFDNY-XFDPNJHTSA-N

SMILES: [Cl-].O=C(O)C1=C(CSC2N1C(=O)C2NC(=O)C(=NOC)C3=NSC(=N3)N)C[N+]=4C=CN5N=CC=CC54

Synonyms:

• (6R,7R)-7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-(methoxyimino)acetamido]-3-(imidazo[1,2-b]pyridazinio-1-ylmethyl)-3-cephem-4-carboxylate hydrochloride
• (6R,7R)-7-[[(2E)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride
• 1,2,4-Thiadiazole, imidazo[1,2-b]pyridazinium deriv.
• 1-{[(6R,7R)-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1H-imidazo[1,2-b]pyridazin-4-ium chloride
• Cefozopran HCl
• Cefozopran monohydrochloride
• Firstcin
• Imidazo[1,2-b]pyridazinium, 1-[[(6R,7R)-7-[[(2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride
• Imidazo[1,2-b]pyridazinium, 1-[[(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride (1:1)
• Imidazo[1,2-b]pyridazinium, 1-[[7-[[(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride, [6R-[6α,7β(Z)]]-
• SCE-2787.HCl
• [6R-[6alpha,7beta(Z)]]-1-[[7-[[(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1H-imidazo[1,2-b]pyridazinium chloride

Imidazo[1,2-b]pyridazinium, 1-[[(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride (1:1)

CAS: 113981-44-5

• Formula: C₁₉H₁₈ClN₉O₅S₂
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 551.9865

Cefozopran hydrochloride

CAS: 113981-44-5

Cefozopran hydrochloride

CAS: 113981-44-5

Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin.

• Formula: C₁₉H₁₈ClN₉O₅S₂
• Purity: 95.34%
• Color and Shape: Solid
• Molecular weight: 551.99

Cefozopran Hydrochloride RS

CAS: 113981-44-5

• Color and Shape: White To Pale Yellow

Cefozopran hydrochloride

CAS: 113981-44-5

Cefozopran hydrochloride is a prodrug of cefozopran that is converted to its active form in …

• Formula: C₁₉H₁₈ClN₉O₅S₂
• Purity: Min. 95%
• Molecular weight: 551.99 g/mol