CAS 115074-43-6: Calcium mupirocin dihydrate

Description: Calcium mupirocin dihydrate is a calcium salt of mupirocin, an antibiotic derived from the bacterium Pseudomonas fluorescens. It is primarily used in topical formulations for the treatment of skin infections, particularly those caused by Staphylococcus aureus, including methicillin-resistant strains (MRSA). The dihydrate form indicates that the compound contains two molecules of water for each molecule of calcium mupirocin, which can influence its solubility and stability. This substance typically appears as a white to off-white powder and is characterized by its ability to inhibit bacterial protein synthesis by binding to bacterial isoleucyl-tRNA synthetase. Its pharmacological properties include a broad spectrum of activity against gram-positive bacteria, making it effective in treating localized infections. Additionally, calcium mupirocin dihydrate is often formulated in ointments or creams for easy application to affected areas. Safety and efficacy profiles are well-established, but like all antibiotics, it should be used judiciously to prevent the development of resistance.

Formula: C₂₆H₄₄O₉Ca·H₂O

InChI: InChI=1S/C26H44O9.Ca.H2O/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);;1H2/b16-13+;;/t17-,18-,19-,20-,21-,24+,25-,26-;;/m0../s1

InChI key: InChIKey=BLZJSZDYKXDOEQ-MJJSANMQSA-N

SMILES: [Ca].O=C(O)CCCCCCCCOC(=O)C=C(C)CC1OCC(CC2OC2C(C)C(O)C)C(O)C1O.O

Synonyms:

• <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[(2S,3S)-[3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, calcium salt, hydrate (2:1:2)
• <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, calcium salt (2:1), dihydrate, [2E,8[2S,3S(1S,2S)]]-
• Calcium mupirocin dihydrate
• L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, calcium salt (2:1), dihydrate, [2E,8[2S,3S(1S,2S)]]-
• Mupirocin Calcium Hydrate
• Mupirocin calcium dihydrate
• calcium 9-[(E)-4-[3,4-dihydroxy-5-[[3-(2-hydroxy-1-methyl-propyl)oxiran-2-yl]methyl]tetrahydropyran-2-yl]-3-methyl-but-2-enoyl]oxynonanoic acid dihydrate
• L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[(2S,3S)-[3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, calcium salt, hydrate (2:1:2)

Mupirocin Calcium

CAS: 115074-43-6

Antibiotics nesoi

• Formula: C₅₂H₈₆CaO₁₈· 2H₂O
• Color and Shape: White Powder
• Molecular weight: 1038.54401

L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[(2S,3S)-[3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, calcium salt, hydrate (2:1:2)

CAS: 115074-43-6

• Formula: C₅₂H₉₂CaO₂₀
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 1077.3529

Mupirocin calcium salt

CAS: 115074-43-6

• Formula: C₅₂H₈₆CaO₁₈·xH₂O
• Purity: 865 - 936 μg/mg (Mupirocin)
• Color and Shape: White to off-white powder
• Molecular weight: 1039.30 (anhydrous)

Mupirocin Calcium Dihydrate

CAS: 115074-43-6

• Formula: C₂₆H₄₃O₉·CaH₂O
• Color and Shape: Neat
• Molecular weight: 1075.34

Mupirocin calcium hydrate

CAS: 115074-43-6

Mupirocin calcium hydrate is an antibiotic, showed a high level of activity against staphylococci and …

• Formula: C₅₂H₈₆CaO₁₈·2H₂O
• Purity: 99.01%
• Color and Shape: White To Off-White Crystalline Powder
• Molecular weight: 1075.34

Mupirocin Calcium Salt

CAS: 115074-43-6

• Formula: C₂₆H₄₃O₉·CaH₂O
• Color and Shape: White Solid
• Molecular weight: 1075.34

Mupirocin calcium dihydrate

CAS: 115074-43-6

Inhibitor of isoleucyl-tRNA synthetase; inhibitor of protein synthesis

• Formula: (C₂₆H₄₃O₉)₂•Ca•(H₂O)₂
• Purity: Min. 95%
• Molecular weight: 1,075.34 g/mol