CAS 1154-25-2: EIPA

Description: EIPA, or 5-ethyl-2-(4-(1-pyrrolidinyl)butyl)-1H-imidazole, is a chemical compound characterized by its imidazole structure, which is a five-membered ring containing two nitrogen atoms. It is primarily recognized for its role as a selective inhibitor of the Na+/H+ exchanger, making it significant in various biological and pharmacological studies. EIPA is often utilized in research to investigate cellular processes related to ion transport and pH regulation. The compound is typically a white to off-white solid and is soluble in organic solvents, which facilitates its use in laboratory settings. Its molecular interactions and effects on cellular mechanisms have made it a valuable tool in studies related to cardiovascular health, cancer research, and cellular signaling pathways. As with many chemical substances, proper handling and safety precautions are essential due to potential toxicity and reactivity.

Formula: C₁₁H₁₈ClN₇O

InChI: InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)

InChI key: InChIKey=QDERNBXNXJCIQK-UHFFFAOYSA-N

SMILES: O=C(NC(=N)N)C1=NC(Cl)=C(N=C1N)N(CC)C(C)C

Synonyms:

• 2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-
• 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide
• 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
• Ethylisopropylamiloride
• L 593754
• Mh 12-43
• Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-
• Pyrazinecarboxamide, N-amidino-3-amino-6-chloro-5-(ethylisopropylamino)-
• 5-(N-Ethyl-N-Isopropyl) Amiloride
• 5-(N-Ethyl-N-isopropyl)amiloride

2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-

CAS: 1154-25-2

• Formula: C₁₁H₁₈ClN₇O
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 299.7599

5-(N-Ethyl-N-isopropyl) amiloride

CAS: 1154-25-2

• Formula: C₁₁H₁₈ClN₇O
• Molecular weight: 299.76

EIPA

CAS: 1154-25-2

EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA …

• Formula: C₁₁H₁₈ClN₇O
• Purity: 96.62% - 98.52%
• Color and Shape: Off-White To Yellow Solid
• Molecular weight: 299.76

5-(N-Ethyl-N-isopropyl) Amiloride

CAS: 1154-25-2

Stability Unstable in methanol Applications Selective Na+/H+ antiporter inhibitor. Selectively enhances the excretion of sodium …

• Formula: C₁₁H₁₈ClN₇O
• Color and Shape: Neat
• Molecular weight: 299.76

3-AMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-5-[ETHYL(1-METHYLETHYL)AMINO]-2-PYRAZINECARBOXAMIDE

CAS: 1154-25-2

• Purity: 95.0%
• Molecular weight: 299.760009765625

5-(N-Ethyl-N-isopropyl) amiloride

CAS: 1154-25-2

5-(N-Ethyl-N-isopropyl) amiloride is a cyclase inhibitor that has been shown to have anti-cancer effects in …

• Formula: C₁₁H₁₈ClN₇O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 299.76 g/mol