CAS 1159-82-6: 10-hydroxyamitriptyline

Description:10-Hydroxyamitriptyline is a chemical compound that is a derivative of amitriptyline, which is primarily known as an antidepressant. This substance is characterized by the presence of a hydroxyl group at the 10-position of the dibenzocycloheptene structure, which contributes to its pharmacological properties. It is classified as a tricyclic antidepressant (TCA) and exhibits a range of biological activities, including potential effects on neurotransmitter reuptake, particularly serotonin and norepinephrine. The compound is typically found in a crystalline form and is soluble in organic solvents. Its molecular structure includes multiple aromatic rings, which are common in many pharmaceuticals, enhancing its interaction with biological targets. While 10-hydroxyamitriptyline itself may not be widely used in clinical settings, it serves as an important metabolite of amitriptyline, contributing to the overall pharmacokinetics and therapeutic effects of the parent drug. Research into its specific effects and potential applications continues to evolve within the field of medicinal chemistry.

Formula:C₂₀H₂₃NO

InChI:InChI=1/C20H23NO/c1-21(2)13-7-12-17-16-9-4-3-8-15(16)14-20(22)19-11-6-5-10-18(17)19/h3-6,8-12,20,22H,7,13-14H2,1-2H3/b17-12-

Synonyms:
5H-Dibenzo(a,d)cyclohepten-10-ol, 5-(3-(dimethylamino)propylidene)-10,11-dihydro-
(5Z)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol
10-Hydroxyamitriptyline

Found 5 products.

Product data	Purity	Price range	Estimated delivery
Amitriptyline EP Impurity F (10-Hydroxy Amitriptyline) REF: 4Z-A-209CAS: 1159-82-6	- - -	To inquire	Tue 04 Mar 25
(5EZ,10RS)-5-[3-(Dimethyl-amino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol REF: 86-MM0062.05-0025CAS: 1159-82-6	- - -	To inquire	Tue 04 Mar 25
(5EZ,10RS)-5-[3-(Dimethyl-amino)propylidene]-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol REF: 86-MM0062.05CAS: 1159-82-6	- - -	To inquire	Tue 04 Mar 25
Amitriptyline EP Impurity F-d6 REF: 4Z-A-2015CAS: 1159-82-6	- - -	To inquire	Mon 10 Mar 25
10-Hydroxyamitriptyline REF: 3D-BAA15982CAS: 1159-82-6	Min. 95%	- - -	Discontinued product