CAS 116662-09-0: 1,2-dipalmitoylphosphatidylfluorouridine

Description:1,2-Dipalmitoylphosphatidylfluorouridine is a synthetic phospholipid that incorporates a fluorouridine moiety, which is a modified nucleoside. This compound features two palmitic acid chains, contributing to its amphiphilic nature, allowing it to form lipid bilayers or micelles in aqueous environments. The presence of the fluorouridine component enhances its potential for biological applications, particularly in drug delivery and gene therapy, as it can interact with nucleic acids. The compound is typically used in research settings, particularly in studies involving membrane dynamics, cellular uptake, and the development of lipid-based delivery systems. Its structural characteristics, including the fatty acid chains and the phosphatidyl group, influence its biophysical properties, such as phase behavior and permeability. Additionally, the fluorine atom in the fluorouridine moiety can provide unique spectroscopic properties, making it useful for various analytical techniques. Overall, 1,2-dipalmitoylphosphatidylfluorouridine serves as an important tool in biochemistry and molecular biology research.

Formula:C₄₄H₇₈FN₂O₁₃P

InChI:InChI=1/C44H78FN2O13P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-38(48)56-32-35(59-39(49)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)33-57-61(54,55)58-34-37-40(50)41(51)43(60-37)47-31-36(45)42(52)46-44(47)53/h31,35,37,40-41,43,50-51H,3-30,32-34H2,1-2H3,(H,54,55)(H,46,52,53)/t35-,37-,40-,41-,43-/m1/s1

Synonyms:
1,2-Dppf
5'-Uridylic acid, 5-fluoro-, mono(2,3-bis((1-oxohexadecyl)oxy)propyl) ester, (R)-
5'-O-[{[(2R)-2,3-bis(hexadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-5-fluorouridine