CAS 119665-76-8: SILYLATED ERYTHROMYCIN OXIME KETAL

Description:Silylated erythromycin oxime ketal is a derivative of erythromycin, an antibiotic belonging to the macrolide class, which is primarily used to treat bacterial infections. This compound features a silyl group, which enhances its stability and solubility, making it suitable for various pharmaceutical applications. The oxime functional group indicates the presence of a nitrogen atom bonded to a hydroxyl group and a carbon atom, contributing to its reactivity and potential biological activity. The ketal structure suggests the presence of a cyclic acetal, which can influence the compound's pharmacokinetics and bioavailability. Silylated erythromycin oxime ketal is typically characterized by its molecular weight, solubility in organic solvents, and stability under different pH conditions. Its unique structural modifications may also affect its interaction with bacterial ribosomes, potentially altering its antimicrobial efficacy compared to parent erythromycin. Overall, this compound represents a specialized modification aimed at improving the therapeutic properties of erythromycin while retaining its core antibiotic activity.

Formula:C₄₇H₉₂N₂O₁₄Si₂

InChI:InChI=1/C47H92N2O14Si2/c1-23-34-47(12,53)39(50)29(4)36(48-63-44(8,9)54-15)27(2)25-45(10,52)40(60-43-38(61-64(17,18)19)33(49(13)14)24-28(3)56-43)30(5)37(31(6)42(51)58-34)59-35-26-46(11,55-16)41(32(7)57-35)62-65(20,21)22/h27-35,37-41,43,50,52-53H,23-26H2,1-22H3/b48-36+/t27-,28?,29+,30+,31-,32?,33?,34-,35?,37+,38?,39-,40-,41?,43?,45-,46?,47-/m1/s1

Synonyms:
Silylated
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-({4-(dimethylamino)-6-methyl-3-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-14-ethyl-7,12,13-trihydroxy-4-({4-methoxy-4,6-dimethyl-5-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-10-{[(2-methoxypropan-2-yl)oxy]imino}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one (non-preferred name)

Found 2 products.

Brand	Product data	Purity	Price range	Estimated delivery
	Silylated Erythromycin Oxime Ketal REF: TR-S435040CAS: 119665-76-8	- - -	2,353.00 €	Tue 15 Apr 25
	Silylated erythromycin oxime ketal REF: 3D-UEA66576CAS: 119665-76-8	Min. 95%	- - -	Discontinued product