CAS 1206801-37-7: 3-Pyridinecarboxamide, N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro-6-methyl-2-oxo-, hydrochloride (1:2)

Description: 3-Pyridinecarboxamide, N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro-6-methyl-2-oxo-, hydrochloride (1:2) is a complex organic compound characterized by its multi-functional structure, which includes a pyridinecarboxamide moiety and various aromatic and heterocyclic components. This compound is typically classified as a pharmaceutical intermediate or active ingredient, potentially exhibiting biological activity due to its intricate arrangement of functional groups. The presence of fluorine atoms suggests enhanced lipophilicity and may influence its pharmacokinetic properties. The hydrochloride salt form indicates improved solubility in aqueous environments, which is advantageous for drug formulation. Its molecular structure may allow for interactions with specific biological targets, making it of interest in medicinal chemistry. As with many compounds of this nature, safety and handling precautions are essential, and its stability, reactivity, and potential toxicity would need to be evaluated in a laboratory setting.

Formula: C₃₀H₂₂F₂N₆O₃·2ClH

InChI: InChI=1S/C30H22F2N6O3.2ClH/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19;;/h3-16H,1-2H3,(H,33,34)(H,36,39);2*1H

InChI key: InChIKey=NNYNNMGUBHQQLZ-UHFFFAOYSA-N

SMILES: Cl.O=C(NC1=CC=C(OC2=CC=3C=NN(C3C=C2C=4C=NNC4)C)C(F)=C1)C5=CC=C(N(C5=O)C6=CC=C(F)C=C6)C

Synonyms:

• 3-Pyridinecarboxamide, N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro-6-methyl-2-oxo-, hydrochloride (1:2)

Merestinib dihydrochloride

CAS: 1206801-37-7

Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and …

• Formula: C₃₀H₂₄Cl₂F₂N₆O₃
• Color and Shape: Solid
• Molecular weight: 625.45

LY 2801653 dihydrochloride

CAS: 1206801-37-7

• Formula: C₃₀H₂₄Cl₂F₂N₆O₃
• Purity: 99%
• Molecular weight: 625.4528

N-[3-Fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide dihy drochloride

CAS: 1206801-37-7

N-[3-Fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine 3carboxamide dihydrochloride (LB0802) is a potent and selective inhibitor of cyclin dependent kinases (CDKs). …

• Formula: C₃₀H₂₂F₂N₆O₃•(HCl)₂
• Purity: Min. 95%
• Molecular weight: 625.45 g/mol