CAS 121058-88-6: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

Description: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly for the synthesis of oligonucleotides. This compound features several key functional groups, including a phosphoramidite moiety, which is crucial for the coupling reactions in oligonucleotide synthesis. The presence of protective groups, such as the dimethoxytrityl and tert-butyl dimethylsilyl groups, indicates that this compound is designed to protect reactive sites during synthesis, enhancing stability and solubility. The acetyl group contributes to the overall stability and solubility of the molecule. The cyanoethyl group is involved in the activation of the phosphoramidite for nucleophilic attack during the oligonucleotide assembly process. Overall, this compound exemplifies the sophisticated design of reagents used in modern molecular biology techniques, facilitating the precise construction of DNA and RNA sequences for research and therapeutic applications.

Formula: C₄₇H₆₄N₅O₉PSi

Synonyms:

• 2'-TBDMS-rC(N-Ac) Phosphoramidite
• 5'-O-DMT-2'-TBDMS-rC(N-Ac)-3'-CEDPA
• Ac-rC Phosphoramidite
• N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-cytidine-3'-cyanoethyl Phosphoramidite

Ac-rC Phosphoramidite

CAS: 121058-88-6

• Formula: C₄₇H₆₄N₅O₉PSi
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 902.0984

Ac-Rc Phosphoramidite

CAS: 121058-88-6

• Purity: 0.98
• Molecular weight: 902.10g/mol

Ac-rC Phosphoramidite

CAS: 121058-88-6

Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.

• Formula: C₄₇H₆₄N₅O₉PSi
• Purity: 99.49%
• Color and Shape: Liquid
• Molecular weight: 902.1

N4-Acetyl-2''-O-tert-butyldimethylsilyl-5''-O-DMT-cytidine 3''-CE phosphoramidite

CAS: 121058-88-6

• Formula: C₄₇H₆₄N₅O₉PSi
• Purity: ≥ 98.0%
• Color and Shape: White to light yellow powder
• Molecular weight: 902.10

Ac-rC Phosphoramidite

CAS: 121058-88-6

• Molecular weight: 902.114

N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite

CAS: 121058-88-6

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• Formula: C₄₇H₆₄N₅O₉PSi
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 902.11 g/mol