CAS 1216941-48-8: Paritaprevir

Description: Paritaprevir is an antiviral medication primarily used in the treatment of hepatitis C virus (HCV) infections. It is classified as a protease inhibitor, specifically targeting the NS3/4A protease enzyme, which is crucial for the viral replication process. Paritaprevir is often used in combination with other antiviral agents to enhance its efficacy and reduce the likelihood of resistance. The compound is characterized by its specific molecular structure, which includes a series of functional groups that contribute to its biological activity. It is typically administered orally and is known for its relatively favorable pharmacokinetic profile, including good absorption and metabolism. Paritaprevir is part of combination therapies, such as those including ritonavir, to boost its effectiveness and prolong its action. As with many medications, potential side effects may include fatigue, nausea, and liver enzyme elevations, necessitating monitoring during treatment. Overall, Paritaprevir represents a significant advancement in the management of chronic hepatitis C infections.

Formula: C₄₀H₄₃N₇O₇S

InChI: InChI=1S/C40H43N7O7S/c1-24-21-42-33(22-41-24)35(48)43-32-16-6-4-2-3-5-11-25-20-40(25,39(51)46-55(52,53)27-17-18-27)45-36(49)34-19-26(23-47(34)38(32)50)54-37-30-14-8-7-12-28(30)29-13-9-10-15-31(29)44-37/h5,7-15,21-22,25-27,32,34H,2-4,6,16-20,23H2,1H3,(H,43,48)(H,45,49)(H,46,51)/b11-5-/t25-,26-,32+,34+,40-/m1/s1

InChI key: InChIKey=UAUIUKWPKRJZJV-QPLHLKROSA-N

SMILES: O=C(NC1C(=O)N2CC(OC=3N=C4C=CC=CC4=C5C=CC=CC35)CC2C(=O)NC6(C(=O)NS(=O)(=O)C7CC7)CC6C=CCCCCC1)C8=NC=C(N=C8)C

Synonyms:

• (2R,6S,12Z,13aS,14aR,16aS)-N-(Cyclopropylsulfonyl)-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-pyrazinyl)carbonyl]amino]-5,16-dioxo-2-(6-phenanthridinyloxy)cyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide
• Abt 450
• Cyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, N-(cyclopropylsulfonyl)-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-pyrazinyl)carbonyl]amino]-5,16-dioxo-2-(6-phenanthridinyloxy)-, (2R,6S,12Z,13aS,14aR,16aS)-
• Paritaprevir
• ABT450

Cyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, N-(cyclopropylsulfonyl)-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-pyrazinyl)carbonyl]amino]-5,16-dioxo-2-(6-phenanthridinyloxy)-, (2R,6S,12Z,13aS,14aR,16aS)-

CAS: 1216941-48-8

• Formula: C₄₀H₄₃N₇O₇S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 765.8771

Paritaprevir

CAS: 1216941-48-8

• Formula: C₄₀H₄₃N₇O₇S
• Color and Shape: White To Off-White Solid
• Molecular weight: 765.89

Paritaprevir

CAS: 1216941-48-8

Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 …

• Formula: C₄₀H₄₃N₇O₇S
• Purity: 98.04%
• Color and Shape: Solid
• Molecular weight: 765.88

Paritaprevir-d5

CAS: 1216941-48-8

• Formula: C₄₀H₃₈N₇O₇SD₅
• Molecular weight: 770.93

Paritaprevir

CAS: 1216941-48-8

Applications Paritaprevir is a pharmaceutical drug that is used in the treatment of hepatitis C …

• Formula: C₄₀H₄₃N₇O₇S
• Color and Shape: Neat
• Molecular weight: 765.877

Paritaprevir

CAS: 1216941-48-8

Please enquire for more information about Paritaprevir including the price, delivery time and more detailed …

• Purity: Min. 95%