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CAS 125572-92-1

:

Rotigotine hydrochloride

Description:
Rotigotine hydrochloride is a synthetic dopamine agonist primarily used in the treatment of Parkinson's disease and restless legs syndrome. It acts by stimulating dopamine receptors in the brain, thereby helping to alleviate symptoms associated with these conditions. The substance is characterized by its ability to cross the blood-brain barrier, which is crucial for its therapeutic effects. Rotigotine is typically administered via a transdermal patch, allowing for continuous delivery and maintaining stable plasma levels. The chemical structure includes a chiral center, contributing to its pharmacological activity. As a hydrochloride salt, it is more soluble in water, enhancing its bioavailability. Common side effects may include nausea, dizziness, and somnolence, reflecting its central nervous system activity. Additionally, it is important to monitor for potential interactions with other medications, as well as to consider individual patient factors when prescribing. Overall, Rotigotine hydrochloride represents a significant advancement in the management of dopamine-related disorders.
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