CAS 127-76-4: Acetylsulfathiazole

Description: Acetylsulfathiazole, with the CAS number 127-76-4, is a sulfonamide antibiotic that exhibits antibacterial properties. It is characterized by its sulfonamide functional group, which is essential for its mechanism of action, inhibiting bacterial growth by interfering with folic acid synthesis. The compound is typically a white to off-white crystalline powder, soluble in water and organic solvents, which facilitates its use in various formulations. Acetylsulfathiazole is primarily used in the treatment of bacterial infections, particularly those caused by susceptible strains of bacteria. Its pharmacological profile includes a relatively short half-life, necessitating multiple doses for effective therapeutic outcomes. Additionally, it may exhibit side effects common to sulfonamides, such as allergic reactions or gastrointestinal disturbances. Due to its specific action against bacteria, it has been utilized in both human and veterinary medicine, although its use has declined with the advent of more effective antibiotics. Proper handling and storage conditions are essential to maintain its stability and efficacy.

Formula: C₁₁H₁₁N₃O₃S₂

InChI: InChI=1S/C11H11N3O3S2/c1-8(15)13-9-2-4-10(5-3-9)19(16,17)14-11-12-6-7-18-11/h2-7H,1H3,(H,12,14)(H,13,15)

InChI key: InChIKey=KXNXWINFSDKMHD-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NC=CS2)C

Synonyms:

• 2-(p-Acetamidobenzenesulfonamido)thiazole
• AST
• Acetamide, N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-
• Acetanilide, 4′-(2-thiazolylsulfamoyl)-
• Acetylsulfathiazole
• N-Acetylsulfathiazole
• N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
• N-[4-[(2-Thiazolylamino)sulfonyl]phenyl]acetamide
• N4-acetylsulfathiazole
• N⁴-Acetylsulfathiazole
• Sulfathiazole, acetyl-
• p-Acetylamino-N-(2-thiazolyl)benzenesulfonamide

Acetamide, N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-

CAS: 127-76-4

• Formula: C₁₁H₁₁N₃O₃S₂
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 297.3533

N-(4-(N-(Thiazol-2-yl)sulfamoyl)phenyl)acetamide

CAS: 127-76-4

• Purity: 95%
• Molecular weight: 297.3500061035156

N-Acetylsulfathiazole

CAS: 127-76-4

Applications N-Acetylsulfathiazole (~90%) is a metabolite of veterinary drugs found in urine. It is also …

• Formula: C₁₁H₁₁N₃O₃S₂
• Color and Shape: Neat
• Molecular weight: 297.35

N-Acetylsulfathiazole

CAS: 127-76-4

N-Acetylsulfathiazole is a sulfa drug that acts as an inhibitor of bacterial growth. It reacts …

• Formula: C₁₁H₁₁N₃O₃S₂
• Purity: Min. 95%
• Molecular weight: 297.4 g/mol