CAS 128625-52-5: PyBOP

Description:PyBOP, or benzotriazol-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate, is a coupling reagent commonly used in peptide synthesis. It facilitates the formation of peptide bonds by activating carboxylic acids, making them more reactive towards amines. PyBOP is characterized by its high efficiency and mild reaction conditions, which help minimize side reactions and protect sensitive functional groups. It is typically used in solid-phase peptide synthesis and solution-phase reactions. The reagent is known for its stability and ease of handling, often being preferred over other coupling agents due to its ability to provide high yields of the desired peptide products. Additionally, PyBOP is soluble in common organic solvents, which enhances its versatility in various synthetic protocols. However, it is important to handle PyBOP with care, as it can be hazardous, and appropriate safety measures should be taken during its use. Overall, PyBOP is a valuable tool in the field of organic and medicinal chemistry, particularly in the synthesis of complex peptides.

Formula:C₁₈H₂₈N₆OP·F₆P

InChI:InChI=1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1

InChI key:InChIKey=VIAFLMPQBHAMLI-UHFFFAOYSA-N

SMILES:[F-][P+5]([F-])([F-])([F-])([F-])[F-].N1=NN(O[P+](N2CCCC2)(N3CCCC3)N4CCCC4)C=5C=CC=CC15

Synonyms:
(1-Hydroxy-1H-benzotriazolato-O)tri-1-pyrrolidinylphosphorus(1+) hexafluorophosphate(1-)
1-Benzotriazolyloxytripyrrolidinylphosphonium hexafluorophosphate
1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate
1H-Benzotriazole, 1-hydroxy-, phosphorus complex
Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
Benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
Phosphorus(1+), [1-(hydroxy-κO)-1H-benzotriazolato]tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1)
PyBOP
Pyrrolidine, phosphorus complex
See more synonyms

Found 11 products.

Product data	Purity	Price range	Estimated delivery
1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate [Coupling Reagent for Peptide] REF: 3B-B1774CAS: 128625-52-5	>98.0%(HPLC)	71.00 €~233.00 €	Thu 20 Mar 25
1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 98% REF: 02-B25251CAS: 128625-52-5	98%	To inquire	Fri 21 Mar 25
PyBOP REF: 01-4031604CAS: 128625-52-5	- - -	203.00 €~592.00 €	Tue 25 Mar 25
1H-Benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate REF: 10-F009017CAS: 128625-52-5	98.0%	24.00 €~190.00 €	Tue 25 Mar 25
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate REF: IN-DA000Y92CAS: 128625-52-5	98%	To inquire	Thu 27 Mar 25
[(1H-Benzotriazol-1-yl)oxy][tri(pyrrolidin-1-yl)]phosphonium hexafluorophosphate REF: 54-PC1208CAS: 128625-52-5	By hplc: 98.9% by area (Typical Value in Batch COA)	32.00 €~188.00 €	Fri 28 Mar 25
Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate REF: 7W-GE4655CAS: 128625-52-5	≥ 98.0% (anhydrous basis)	38.00 €~292.00 €	Fri 28 Mar 25
PYBOP(R), 99% REF: AC-27072CAS: 128625-52-5	99%	To inquire	Tue 01 Apr 25
Benzotriazol-1-yl-oxytripyrrolidinphosphonium Hexafluorophosphate REF: TR-B207500CAS: 128625-52-5	- - -	159.00 €~308.00 €	Tue 08 Apr 25
PyBOP REF: 3D-KPC-1068-PICAS: 128625-52-5	Min. 95%	140.00 €~658.00 €	Mon 07 Apr 25
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate REF: 3D-FP15550CAS: 128625-52-5	Min. 98 Area-%	180.00 €~4,582.00 €	Mon 07 Apr 25