CAS: 129981-36-8 - Sampatrilat

Formula: C₂₆H₄₀N₄O₉S

InChI: InChI=1S/C26H40N4O9S/c1-40(38,39)30-20(6-2-5-13-27)22(32)28-16-18(23(33)34)15-26(11-3-4-12-26)25(37)29-21(24(35)36)14-17-7-9-19(31)10-8-17/h7-10,18,20-21,30-31H,2-6,11-16,27H2,1H3,(H,28,32)(H,29,37)(H,33,34)(H,35,36)/t18-,20-,21-/m0/s1

InChI key: InChIKey=LPUDGHQMOAHMMF-JBACZVJFSA-N

SMILES: O=C(O)C(NC(=O)C1(CCCC1)CC(C(=O)O)CNC(=O)C(NS(=O)(=O)C)CCCCN)CC2=CC=C(O)C=C2

Synonyms:

• beta-Alanine, 2-((1-(((1-carboxy-2-(4-hydroxyphenyl)ethyl)amino)carbonyl)cyclopentyl)methyl)-N-(N2-(methylsulfonyl)-L-lysyl)-, (S-(R*,R*))-
• N-({1-[(2R)-3-carboxy-2-{[N~2~-(methylsulfonyl)-L-lysyl]amino}propyl]cyclopentyl}carbonyl)-L-tyrosine
• L-Tyrosine, N2-(methylsulfonyl)-L-lysyl-1-[(2S)-3-amino-2-carboxypropyl]cyclopentanecarbonyl-
• N-(1-(2-Carboxy-3-(N(2)-mesyllysylamino)propyl)-1-cyclopentylcarbonyl)tyrosine
• (S-(R*,R*))-2-((1-(((1-Carboxy-2-(4-hydroxyphenyl)ethyl)amino)carbonyl)cyclopentyl)methyl)-N-(N2-(methylsulfonyl)-L-lysyl)-beta-Alanine
• UK 81252
• β-Alanine, 2-[[1-[[[1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]carbonyl]cyclopentyl]methyl]-N-[N2-(methylsulfonyl)-L-lysyl]-, [S-(R*,R*)]-
• N2-(Methylsulfonyl)-L-lysyl-1-[(2S)-3-amino-2-carboxypropyl]cyclopentanecarbonyl-L-tyrosine
• N-((1-((S)-3-((S)-6-Amino-2-methanesulfonamidohexanamido)-2-carboxypropyl)cyclopentyl)carbonyl)-L-tyrosine
• Sampatrilat
• UK 81,252

Sampatrilat

CAS: 129981-36-8

Sampatrilat, an oral vasopeptidase inhibitor, more potently blocks C-domain ACE (Ki=13.8 nM) over N-domain (Ki=171.9 …

• Formula: C₂₆H₄₀N₄O₉S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 584.68