CAS 130521-05-0: 3,3-difluoroglutamate

Description: 3,3-Difluoroglutamate is a fluorinated derivative of glutamate, an important amino acid that functions as a neurotransmitter in the central nervous system. This compound features two fluorine atoms substituted at the 3-position of the glutamate backbone, which can significantly influence its biochemical properties and interactions. The presence of fluorine can enhance the lipophilicity and metabolic stability of the molecule, potentially affecting its biological activity and pharmacokinetics. 3,3-Difluoroglutamate may exhibit altered binding affinity to glutamate receptors compared to its non-fluorinated counterpart, making it of interest in neuropharmacology and medicinal chemistry. Additionally, its structural modifications could provide insights into the design of novel therapeutic agents targeting glutamate-related pathways. As with many fluorinated compounds, considerations regarding its environmental impact and toxicity are essential in its application and study. Overall, 3,3-difluoroglutamate represents a unique chemical entity with potential implications in both research and therapeutic contexts.

Formula: C₅H₇F₂NO₄

InChI: InChI=1/C5H7F2NO4/c6-5(7,1-2(9)10)3(8)4(11)12/h3H,1,8H2,(H,9,10)(H,11,12)

Synonyms:

• 3,3-Difluoro-DL-glutamic acid
• DL-beta,beta-Difluoroglutamic acid
• F2Glu
• DL-Glutamic acid, 3,3-difluoro-
• 3,3-Difluoroglutamic Acid
• 3,3-Difluoroglutamate

Glutamic acid, 3,3-difluoro-

CAS: 130521-05-0

• Formula: C₅H₇F₂NO₄
• Molecular weight: 183.1102

2-Amino-3,3-Difluoropentanedioic Acid

CAS: 130521-05-0

2-Amino-3,3-difluoropentanedioic acid (2ADPA) is a potent inhibitor of the enzyme glutaminase, which converts glutamate to …

• Formula: C₅H₇F₂NO₄
• Purity: Min. 95%
• Molecular weight: 183.11 g/mol