Description:Fmoc-N-Me-Abu-OH, also known as Fmoc-N-methyl-α-aminobutyric acid, is a chemical compound commonly used in peptide synthesis and drug development. It features a fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is widely utilized to protect amino groups during the synthesis of peptides. The presence of the N-methyl group enhances its steric properties and can influence the conformation of peptides. The α-aminobutyric acid (Abu) moiety contributes to the compound's hydrophobic characteristics, making it useful in the design of peptides with specific structural and functional properties. Fmoc-N-Me-Abu-OH is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its stability under standard laboratory conditions allows for its use in various synthetic protocols. Overall, this compound is significant in the field of medicinal chemistry and peptide research due to its unique structural features and functional versatility.
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