CAS 133627-24-4: 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one

Description: 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, with CAS number 133627-24-4, is a complex organic compound characterized by its bicyclic structure, which incorporates both diazepine and pyridine moieties. This compound features a cyclopropyl group, contributing to its unique steric and electronic properties. The presence of a hydroxymethyl group enhances its potential for hydrogen bonding, which may influence its solubility and reactivity. The overall structure suggests potential biological activity, possibly as a pharmacological agent, given the presence of nitrogen-containing rings that are often associated with medicinal chemistry. Its synthesis and characterization would typically involve advanced organic synthesis techniques, and its properties can be further explored through spectroscopic methods such as NMR and mass spectrometry. The compound's specific applications and interactions would depend on ongoing research, particularly in the fields of medicinal chemistry and drug development.

Formula: C₁₅H₁₄N₄O₂

InChI: InChI=1S/C15H14N4O2/c20-8-9-5-7-17-14-12(9)18-15(21)11-2-1-6-16-13(11)19(14)10-3-4-10/h1-2,5-7,10,20H,3-4,8H2,(H,18,21)

InChI key: InChIKey=SEBABOMFNCVZGF-UHFFFAOYSA-N

SMILES: O=C1NC=2C(=NC=CC2CO)N(C3=NC=CC=C13)C4CC4

Synonyms:

• 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
• 12-Hydroxy nevirapine
• 6H-Dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-
• 6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-

12-Hydroxynevirapine

CAS: 133627-24-4

12-Hydroxynevirapine, major Nevirapine metabolite; non-toxic but liver/skin SULTs convert it to reactive 12-Sulphoxy-nevirapine.

• Formula: C₁₅H₁₄N₄O₂
• Color and Shape: Liquid
• Molecular weight: 282.3

12-hydroxy Nevirapine

CAS: 133627-24-4

• Formula: C₁₅H₁₄N₄O₂
• Molecular weight: 282.30

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

CAS: 133627-24-4

• Formula: C₁₅H₁₄N₄O₂
• Color and Shape: Neat
• Molecular weight: 282.3

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-B:2',3'-E][1,4]diazepin-6-one

CAS: 133627-24-4

Nevirapine is a non-nucleoside reverse transcriptase inhibitor that is used to treat HIV infection. It …

• Formula: C₁₅H₁₄N₄O₂
• Purity: Min. 95%
• Molecular weight: 282.3 g/mol