CAS 136033-49-3: Nexopamil

Description:Nexopamil is a chemical compound classified as a calcium channel blocker, primarily used in the treatment of hypertension and certain types of angina. It functions by inhibiting the influx of calcium ions through L-type calcium channels in cardiac and smooth muscle cells, leading to vasodilation and a reduction in heart rate. This mechanism helps to lower blood pressure and alleviate chest pain associated with angina. Nexopamil is characterized by its specific molecular structure, which includes a unique arrangement of atoms that contributes to its pharmacological properties. The compound is typically administered in a controlled dosage to manage cardiovascular conditions effectively. As with other calcium channel blockers, potential side effects may include dizziness, headache, and peripheral edema. It is essential for patients to consult healthcare professionals for appropriate usage and to monitor for any adverse reactions. Overall, Nexopamil represents a significant therapeutic option within the class of calcium channel blockers, contributing to cardiovascular health management.

Formula:C₂₄H₄₀N₂O₃

InChI:InChI=1/C24H40N2O3/c1-8-9-10-11-14-26(4)15-12-13-24(18-25,19(2)3)20-16-21(27-5)23(29-7)22(17-20)28-6/h16-17,19H,8-15H2,1-7H3/t24-/m0/s1

Synonyms:
(2S)-5-(Hexylmethylamino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile
(2S)-5-[hexyl(methyl)amino]-2-(propan-2-yl)-2-(3,4,5-trimethoxyphenyl)pentanenitrile
Nexopamil [INN]
UNII-ECA0E1PO91